Lupus Loophole Turns Out to be Dead-End
Even though pediatric lupus patients are at increased risk of developing heart disease as adults, statin drugs, which lower cholesterol, do not provide enough benefit to warrant use in these patients. Children with lupus, an autoimmune disease that causes widespread inflammation and organ damage, often exhibit early signs of atherosclerosis (hardening of the arteries) putting them at risk of heart attack and stroke. Researchers at Duke University Medical Center wanted to find a way to lower this risk and turned to statin drugs for the study. The randomized trial included 221 partici...
Flipping Off Inflammation
A "master switch" protein in white blood cells has been found to influence whether the cells promote or hinder inflammation, according to a new study.