Inspra

Inspra treats high blood pressure. Avoid salt substitutes containing potassium.

Inspra Overview

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Inspra is a prescription medication used to treat high blood pressure. Inspra belongs to a group of drugs called mineralocorticoid receptor blockers. These work by blocking the action of aldosterone, a natural substance in the body that raises blood pressure.

This medication comes in tablet form and is taken once or twice a day, with or without food.

Common side effects of Inspra include diarrhea, coughing, fatigue, and hedache. Inspra can also cause dizziness. Do not drive or operate heavy machinery until you know how Inspra affects you.

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  • Hypertension

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Inspra Cautionary Labels

precautionsprecautions

Uses of Inspra

Inspra is a prescription medication used to treat high blood pressure.

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

Manufacturer

Inspra Drug Class

Inspra is part of the drug class:

Side Effects of Inspra

Serious side effects have been reported with Inspra. See the "Inspra Precautions" section.

Common side effects of Inspra include:

  • diarrhea
  • coughing
  • fatigue
  • dizziness
  • flu-like symptoms
  • increased potassium levels

This is not a complete list of Inspra side effects.Ask your doctor or pharmacist for more information.

Tell your doctor if you have any side effect that bothers you or that does not go away. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-FDA-1088.

Inspra Interactions

Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your doctor if you take:

  • angiotensin converting enzyme (ACE) inhibitors such as benazepril (Lotensin), captopril (Capoten), enalapril (Vasotec), fosinopril (Monopril), lisinopril (Prinivil, Zestril), and quinapril (Accupril)
  • angiotensin II receptor antagonists such as eprosartan (Teveten), irbesartan (Avapro), losartan (Cozaar), olmesartan (Benicar), and valsartan (Diovan)
  • aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Advil, Motrin) and naproxen (Aleve, Naprosyn)
  • cimetidine (Tagamet)
  • clarithromycin (Biaxin)
  • danazol (Danocrine)
  • delavirdine (Rescriptor)
  • diltiazem (Cardizem, Dilacor, Tiazac)
  • erythromycin (E.E.S., E-Mycin, Erythrocin)
  • fluconazole (Diflucan)
  • fluoxetine (Prozac, Sarafem)
  • fluvoxamine (Luvox)
  • HIV protease inhibitors such as indinavir (Crixivan), ritonavir (Norvir), and saquinavir (Fortovase, Invirase)
  • isoniazid (INH, Nydrazid)
  • lithium (Eskalith, Lithobid)
  • metronidazole (Flagyl)
  • nefazodone (Serzone)
  • nelfinavir (Viracept)
  • troleandomycin (TAO)
  • verapamil (Calan, Covera, Isoptin, Verelan)
  • zafirlukast (Accolate)
  • St. John's Wort

This is not a complete list of Inspra drug interactions. Ask your doctor or pharmacist for more information.

Inspra Precautions

Serious side effects have been reported with Inspra, including:

  • chest pain
  • tingling in the arms and legs
  • loss of muscle tone
  • weakness of heaviness in legs
  • confusion
  • lack of energy
  • cold, gray skin
  • irregular heartbeat

Inspra can cause dizziness. Do not drive or operate heavy machinery until you know how Inspra affects you.

Do not take Inspra if you:

  • are allergic to Inspra or to any of its ingredients
  • have a high potassium level in your blood
  • have decreased kidney function
  • are taking medications that inhibit the CYP3A4 enzyme, including ketoconazole (Nizoral), clarithromycin (Biaxin), nefazodone (Serzone), ritonavir (Norvir), and nelfinavir (Viracept)
  • have type 2 diabetes with microalbuminuria
  • have increased levels of creatinine in your blood
  • are taking potassium supplements or other medications that can increase the level of potassium in your blood

Inspra Food Interactions

Medications can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of Inspra, salt substitutes containing potassium should be avoided.

Your doctor may also prescribe a low-salt diet; follow these instructions carefully.

Inform MD

Before taking Inspra, tell your doctor about all of your medical conditions. Especially tell your doctor if you:

  • are allergic to Inspra or to any of its ingredients
  • have or have had high blood levels of potassium
  • have diabetes
  • have gout
  • have liver disease
  • have kidney disease
  • are pregnant or breastfeeding

Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamines, and herbal supplements.

Inspra and Pregnancy

Tell your doctor if you are pregnant or plan to become pregnant.

The FDA categorizes medications based on safety for use during pregnancy. Five categories - A, B, C, D, and X - are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy.

Inspra falls into category B. There are no well-done studies that have been done in humans with Inspra. In animal studies, pregnant animals were given this medication, and the babies did not show any medical issues related to this medication.

Inspra and Lactation

Tell your doctor if you are breastfeeding or plan to breastfeed.

It is not known if Inspra crosses into human milk. Because many medications can cross into human milk and because of the possibility for serious adverse reactions in nursing infants with use of this medication, a choice should be made whether to stop nursing or stop the use of this medication. Your doctor and you will decide if the benefits outweigh the risk of using Inspra.

Inspra Usage

Take Inspra exactly as prescribed.

This medication comes in tablet form and is taken once or twice a day, with or without food.

If you miss a dose, take the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and take your next dose at the regular time. Do not take 2 doses of Inspra at the same time.

Inspra Dosage

Take this medication exactly as prescribed by your doctor. Follow the directions on your prescription label carefully.

The dose your doctor recommends may be based on the following:

  • the condition being treated
  • how you respond to this medication
  • other medications you are taking

The recommended starting dose of Inspra is 50 mg once daily. The dose may be increased to 50 mg 2 times daily based on individual reponse. The maximum recommended dose of Inspra is 100 mg daily.

Inspra Overdose

If you take too much Inspra, call your healthcare provider or local Poison Control Center or seek emergency medical attention right away.

If Inspra is administered by a healthcare provider in a medical setting, it is unlikely that an overdose will occur. However, if overdose is suspected, seek emergency medical attention.

Other Requirements

  • Store Inspra at room temperature.
  • Keep this and all medications out of the reach of children.