Lotensin treats high blood pressure. This medication should not be used during pregnancy. Avoid salt substitutes containing potassium.

Lotensin Overview

Reviewed: September 9, 2013

Lotensin is a prescription medicine used with other medications to treat high blood pressure. Lotensin belongs to a group of medications called angiotensin-converting enzyme (ACE) inhibitors. Lotensin works by blocking the ACE enzyme, which helps blood vessels to relax and lowers blood pressure.

This medication comes in tablet form and is usually taken once or twice daily with water. 
Common side effects include headache, dizziness, fatigue and cough.

Patient Ratings for Lotensin

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  • Diabetic Nephropathies
  • Heart Failure
  • Hypertension
  • Hypertrophy, Left Ventricular
  • Ventricular Dysfunction, Left

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Lotensin Cautionary Labels


Uses of Lotensin

Lotensin is a prescription medication used alone or with other medications to control high blood pressure (hypertension). 

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.


Lotensin Drug Class

Lotensin is part of the drug class:

Side Effects of Lotensin

The most common Lotensin side effects are:

  • headache
  • dizziness
  • tiredness
  • drowsiness
  • nausea
  • cough

Tell your doctor if any of these symptoms are severe or do not go away.

Less common, but more serious Lotensin side effects are:

  • swelling of the face, legs, feet, ankles, arms, lips, tongue, and throat 
  • swelling of the intestines (intestinal angioedema)
  • serious allergic reactions
  • rash
  • decreased kidney function
  • pancreatitis
  • asthma
  • difficulty breathing
  • increased levels of potassium in the blood (hyperkalemia)
  • anemia
  • increased risk of infections
  • liver failure

This is not a complete list of Lotensin side effects. Ask your doctor or pharmacist for more information. Tell your doctor if you develop any side effects.

Lotensin Interactions

Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamin, and herbal supplements. Especially tell your doctor if you take:

  • diuretics 
  • potassium-sparing diuretics
  • potassium supplements
  • lithium (Eskalith, Lithobid)
  • NSAIDs
  • injectable gold (sodium aurothiomalate)

This is not a complete list of Lotensin drug interactions. Ask your doctor or pharmacist for more information.

Lotensin Precautions

Do not take Lotensin if you are allergic to any of the ingredients. Each manufacturer may use different inactive ingredients. Ask your doctor or pharmacist for a complete list. Tell your doctor if you are allergic to any other ACE inhibitors.

Do not take Lotensin if you have ever had angioedema, with or without prior ACE inhibitor treatment.

Lotensin , if taken while pregnant, can harm or cause death to the unborn baby. Tell your doctor right away if you become pregnant while taking this medication.

ACE inhibitors, including Lotensin, have caused liver failure. While this is rare, be sure to tell your doctor right away if you show symptoms of liver damage including nausea, lack of appetite, tiredness, diarrhea, yellowing of skin or eyes (jaundice), stomach pain, flu-like symptoms, and bleeding easily.

Lotensin may cause extreme low blood pressure. The symptoms are lightheadedness, dizziness, and fainting. Until you know how Lotensin affects you, do not drive or operate heavy machinery. Extreme low blood pressure is more likely to happen if you:

  • are taking a diuretic
  • are on dialysis
  • have diarrhea
  • are vomiting
  • are not drinking enough liquids
  • are sweating a lot

Lotensin Food Interactions

Talk to your doctor if you are on a low-salt diet and you are using salt substitutes. Some of these products contain potassium and when taken with Lotensin may lead to a serious condition in which there is too much potassium in the blood (hyperkalemia).

Inform MD

Tell your doctor if you are allergic to Lotensin or any other ACE inhibitors.

Tell your doctor if you have:

  • diabetes
  • heart disease including congestive heart failure
  • kidney disease
  • lupus
  • scleroderma
  • a history of angioedema

Tell your doctor if you are pregnant or breastfeeding. Also, let your doctor know if you are on dialysis or will be undergoing surgery or anesthesia.

Tell your doctor about all the medications you take including prescription and non-prescription medicines, vitamins, and herbal supplements.




Lotensin and Pregnancy

Tell your doctor if you are pregnant or plan to become pregnant. Lotensin may cause harm to your unborn baby. If you become pregnant while taking Lotensin, tell your doctor right away.

Lotensin and Lactation

Tell your doctor if you are breastfeeding or plan to breastfeed. Small amounts of Lotensin may be excreted in human breast milk. The effects are unknown.

Lotensin Usage

Lotensin comes as a tablet to be taken by mouth, usually once or twice a day, with water. It can be taken with or without food. If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not take two doses at one time. To help you remember to take your dose, and to maintain even blood levels of Lotensin, take it at the same time every day.

Lotensin Dosage

Take Lotensin exactly as prescribed. Follow the directions on your prescription label carefully. Your doctor will determine the best dose for you based on your age, other medical conditions you have, and other medications you take.

To treat high blood pressure in adults, the recommended starting dose of Lotensin is 10 mg. The normal daily dose is 20 mg to 40 mg. The dose can be divided. This means that if your daily dose is 20 mg, it can be taken as 10 mg twice daily (to reach 20 mg daily). 

The dose of Lotensin for children is based on weight. The recommended starting dose of Lotensin for children six years of age and older is 0.2 mg/kg taken once a day.

Lotensin Overdose

If you take too much Lotensin, call your local Poison Control Center or seek emergency medical attention right away.

Other Requirements

Store Lotensin tablets at room temperature, away from excess light and moisture.

Keep this and all medications out of the reach of children.

Lotensin FDA Warning


When pregnancy is detected, discontinue Lotensin as soon as possible.

Drugs that act directly on the renin-angiotensin system can cause injury and death to the developing fetus.