Xiidra

Xiidra is an eye drop used to treat the symptoms of dry eye disease. If you wear contact lenses, remove them before using Xiidra and wait for at least 15 minutes before placing them back in your eyes.

Xiidra Overview

Reviewed: July 12, 2016
Updated: 

Xiidra is a prescription eye drop solution used to treat the signs and symptoms of dry eye disease (DED). Xiidra is the first medication in a group of medications known as lymphocyte function-associated antigen-1 (LFA-1) antagonists. The mechanism by which Xiidra treats the symptoms of dry eye disease is not yet fully understood.

Xiidra comes in an eyedrop form and is administered as one drop in each eye, two times a day, about 12 hours apart.

Common side effects of Xiidra include eye burning, itching, and redness.

Xiidra can also cause blurred vision. Do not take drive or operate heavy machinery until you know how Xiidra affects you.

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Xiidra Cautionary Labels

precautions

Uses of Xiidra

Xiidra is a prescription eye drop solution used to treat the signs and symptoms of dry eye disease (DED).

It is not known if Xiidra is safe and effective in children under 17 years of age.

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

Manufacturer

Lifitegrast

For more information on this medication choose from the list of selections below.

Side Effects of Xiidra

Serious side effects have been reported with Xiidra. See the “Xiidra Precautions” section.

The most common side effects of Xiidra include:

  • eye irritation
  • eye discomfort
  • blurred vision
  • an unusual taste sensation (dysgeusia)

This is not a complete list of Xiidra side effects. Ask your doctor or pharmacist for more information.

Tell your doctor if you have any side effect that bothers you or that does not go away.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Xiidra Interactions

No drug interactions have been determined by the manufacturer. However, you should tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. Not all drug interactions are known or reported and new drug interactions are continually being reported.

Xiidra Precautions

Do not take Xiidra if you are allergic to Xiidra or to any of its ingredients.

Xiidra Food Interactions

Medications can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of Xiidra, there are no specific foods that you must exclude from your diet when receiving this medication.

Inform MD

Before taking Xiidra, tell your doctor about all of your medical conditions. Especially tell your doctor if you:

  • are allergic to Xiidra or to any of its ingredients
  • are using any other eye drops
  • wear contact lenses
  • are pregnant or plan to become pregnant. It is not known if Xiidra will harm your unborn baby.
  • are breastfeeding or plan to breastfeed. It is not known if Xiidra passes into your breast milk. Talk to your doctor about the best way to feed your baby if you use Xiidra.

Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements.

 

Xiidra and Pregnancy

Tell your doctor if you are pregnant or plan to become pregnant.

There are no well-done studies that have been done in humans with Xiidra. In animal studies, pregnant animals were given this medication, and the babies did not show any medical issues related to this medication.

Xiidra and Lactation

Tell your doctor if you are breastfeeding or plan to breastfeed.

It is not known if Xiidra crosses into human milk. Because many medications can cross into human milk and because of the possibility for serious adverse reactions in nursing infants with the use of this medication, a choice should be made whether to stop nursing or stop the use of this medication. Your doctor and you will decide if the benefits outweigh the risk of using Xiidra.

Xiidra Usage

  • Use Xiidra exactly as your doctor prescribed.
  • Use 1 drop of Xiidra in each eye, 2 times each day, about 12 hours apart.
  • Use Xiidra right away after opening.
  • Throw away the single-use container and any unused solution after you have applied the dose to both eyes.
  • Do not save any unused Xiidra for later.

Xiidra Dosage

Use this medication exactly as prescribed by your doctor. Follow the directions on your prescription label carefully.

The recommended dose of Xiidra for the treatment of dry eye disease (DED) is 1 drop into each eye twice daily (about 12 hours apart).

Xiidra Overdose

If you use too much Xiidra, call your healthcare provider or local Poison Control Center, or seek emergency medical attention right away.

Other Requirements

  • Store Xiidra at room temperature between 68°F to 77°F (20°C to 25°C). 
  • Store Xiidra in the original foil pouch to protect it from light.
  • Do not open the Xiidra foil pouch until you are ready to use the eye drops.
  • Return unused single use containers to their original foil pouch to protect from excessive light exposure.
  • Keep Xiidra and all medicines out of the reach of children.