Vyzulta

Vyzulta lowers eye pressure in people with high eye pressure or open angle glaucoma. Vyzulta may cause eye pigmentation and eyelash changes.

Vyzulta Overview

Reviewed: November 21, 2017
Updated: 

Vyzulta is a prescription medication used to treat open-angle galucoma or ocular hypertension (higher than normal pressure inside the eye), which can lead to glaucoma if not treated.

Vyzulta  belongs to a group of drugs called prostaglandin analogues. It works by increasing the amount of fluid that flows out of the eye in order to lower the pressure.

This medication comes in the form of an eye drop. The usual dose is one drop in the affected eye(s) once daily in the evening.

Common side effects include eye redness, eye irritation and eye pain. Vyzulta can also cause blurred vision. Do not drive or operate heavy machinery until you know how Vyzulta affects you.

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Vyzulta Cautionary Labels

precautions

Uses of Vyzulta

Vyzulta is a prescription medication used to treat open-angle galucoma or ocular hypertension (higher than normal pressure inside the eye), which can lead to glaucoma if not treated.

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

Latanoprostene Bunod

For more information on this medication choose from the list of selections below.

Vyzulta Drug Class

Vyzulta is part of the drug class:

Side Effects of Vyzulta

Serious side effects have been reported with Vyzulta. See the "Vyzulta Precautions” section.

Common side effects of Vyzulta include the following:

  • eye redness
  • eye irritation
  • eye pain

This is not a complete list of Vyzulta side effects. Ask your doctor or pharmacist for more information.

Tell your doctor if you have any side effects that bother you or that do not go away.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Vyzulta Interactions

No drug interactions have been determined by the manufacturer. However, you should tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. Not all drug interactions are known or reported and new drug interactions are continually being reported.

Vyzulta Precautions

Serious side effects have been reported with Vyzulta including the following:

  • eye pigmentation. Vyzulta may cause increased brown pigmentation of the iris, which may be permanent. Eyelid skin darkening may occur, and may be reversible after discontinuation of latanoprost.
  • eyelash changes. Eyelash changes may occur, including increased growth and thickness. Eyelash changes are usually reversible upon discontinuation of treatment.
  • eye or eyelid reactions. If you have any sudden change in vision, pinkeye, or eyelid reactions, call your healthcare provider immediately.

If you develop an intercurrent ocular condition (e.g., trauma or infection) or have ocular surgery, you should immediately seek your doctor's advice concerning the continued use of the multiple-dose container.

Do not drive or operate heavy machinery until you know how Vyzulta affects you.

Do not take Vyzulta if you are allergic to Vyzulta or to any of its ingredients.

Vyzulta Food Interactions

Medications can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of Vyzulta, there are no specific foods that you must exclude from your diet when receiving this medication.

Inform MD

Before taking Vyzulta, tell your doctor about all of your medical conditions. Especially tell your doctor if you:

  • are allergic to Vyzulta or to any of its ingredients
  • have or have had any eye or vision problems
  • are pregnant or plan to become pregnant
  • are breastfeeding or plan to breastfeed

Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements.

Vyzulta and Pregnancy

Tell your doctor if you are pregnant or plan to become pregnant.

In animal studies, pregnant animals were given this medication into the vein and had some babies born with problems. No well-controlled studies have been done in humans. Therefore, this medication may be used if the potential benefits to the mother outweigh the potential risks to the unborn child.

Vyzulta and Lactation

Tell your doctor if you are breastfeeding or plan to breastfeed.

It is not known if Vyzulta crosses into human milk. Because many medications can cross into human milk and because of the possibility for serious adverse reactions in nursing infants with use of this medication, a choice should be made whether to stop nursing or stop the use of this medication. Your doctor and you will decide if the benefits outweigh the risk of using Vyzulta.

Vyzulta Usage

To administer Vyzulta drops:

  1. After washing your hands thoroughly, hold the bottle in one hand, resting your thumb against your eyebrow or the bridge of your nose.
  2. Use the index finger of your other hand to gently pull down your lower lid and make a pocket for the drop.
  3. Gently squeeze the bottle to dispense 1 drop into the pocket of your lower lid.

Don't stop using Vyzulta once your eye pressure is under control unless your eye doctor has told you to do so. Daily use of Vyzulta can help keep your eye pressure down.

Avoid allowing the tip of the dispensing container to contact the eye or surrounding structures because this could cause the tip to become contaminated by common bacteria known to cause ocular infections. Serious damage to the eye and subsequent loss of vision may result from using contaminated solutions.

If you miss a dose, take the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and take your next dose at the regular time. Do not take two doses of Vyzulta at the same time.

Tips for using eye drops

  • If you use more than 1 eye drop medicine, wait at least 5 minutes between each eye drop
  • If you forget to use Vyzulta one day, apply the next drop as usual the next day. Don't try to catch up by using 2 drops the next day. Track your eye drops with the "Eye Pressure and Usage Tracker".
  • If you wear contact lenses, remove your lenses before using Vyzulta and wait 15 minutes after dosing before putting them back in
  • Always wash your hands before using eye drops, or touching your eyes, contacts, or the Vyzulta bottle. Use soap and warm running water to create a lather. Rub your hands together for at least 20 seconds—wash the fronts and backs of your hands, your wrists, between your fingers, and under fingernails. Use either a clean, dry towel or a fresh disposable towel to thoroughly dry your hands. And use a towel to turn off the faucet
  • Remember, to avoid contamination do not touch the dispenser with your hands, eyes, and other surfaces
  • If you have trouble getting the drop into your eye, try turning your head to the side, or lying down. Then place a drop in the inner corner of your eyelid, and open your eye slowly. The drop should roll right into your eye
  • If you find that pulling down on your lower eyelid to make a pocket for the drop is difficult, try gently pinching the eyelid instead—then just drop the medicine into the pocket you created
  • If you tend to blink before the drop hits your eye, try looking to the side rather than straight at the dropper
  • If you aren't sure that you are getting the drop into your eye, try placing the bottle in the refrigerator before use. When you feel the cool eye drop, you will know that it made it into your eye
  • If your hand is shaking, try resting your hand on your face—this may help steady your hand. If that doesn't work, try wearing a light wrist weight

Vyzulta Dosage

The recommended dosage of Vyzulta to lower eye pressure is one drop in the affected eye(s) once daily in the evening. Do not administer Vyzulta more than once daily.

Vyzulta Overdose

If you take too much Vyzulta, call your healthcare provider or local Poison Control Center, or seek emergency medical attention right away.

Other Requirements

  • Store unopened bottle(s) under refrigeration at 2° to 8°C (36° to 46°F). Do not freeze.
  • Once a bottle is opened for use, it may be stored at room temperature up to 25°C (77°F) for 8 weeks.
  • Protect from light.
  • Keep Vyzulta and all medicines out of the reach of children.