Qbrelis, available as an oral solution, treats high blood pressure in children and adults. Qbrelis is not safe to take during pregnancy.
Qbrelis is a prescription medication used to treat high blood pressure in adults and children over 6 years old.
Qbrelis belongs to a class of medications cause angiotensin-converting enzyme (ACE) inhibitors. These medications work by decreasing certain chemicals that tighten the blood vessels, so blood flows more smoothly and the heart can pump blood better.
Qbrelis comes in an oral solution form to be taken by mouth once daily.
Common side effects of Qbrelis include headache, low blood pressure, chest pain, and cough.
Qbrelis may cause dizziness. Do not drive or operate heavy machinery until you know how Qbrelis affects you.
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Uses of Qbrelis
Qbrelis is a prescription medication used to treat:
- high blood pressure in adults and children 6 years of age and older
- in combination with other medications to treat heart failure
- those who have just had an acute myocardial infarction (heart attack)
This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.
Side Effects of Qbrelis
Serious side effects have been reported with Qbrelis. See the “Qbrelis Precautions” section.
Common side effects of Qbrelis include the following:
- Low blood pressure
- Chest pain
This is not a complete list of Qbrelis side effects. Ask your doctor or pharmacist for more information.
Tell your doctor if you have any side effect that bothers you or that does not go away.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your doctor if you take:
- Diuretics including:
- Certain medications used to treat diabetes
- Nonsteroidal anti-inflammatory drugs (NSAIDs) such as aspirin, ibuprofen, and naproxen.
- Lithium (Eskalith, Lithobid)
- Injectable gold (sodium aurothiomalate)
This is not a complete list of Qbrelis drug interactions. Ask your doctor or pharmacist for more information.
Serious side effects have been reported with Qbrelis including the following:
Harm to your unborn baby. Tell your healthcare provider if you are pregnant or become pregnant. It is not safe to take Qbrelis during pregnancy as it can cause serious birth defects and miscarriage.
Angioedema and anaphylaxis (severe allergic reaction). Tell your healthcare provider right away if you have any of the following signs or symptoms:
- swelling of face, eyes, lips, tongue, and arms/legs
- difficulty in swallowing or breathing
Kidney problems. Qbrelis may change the way the kidneys work. Your doctor may want to monitor your kidney functions with certain blood tests as well.
Low blood pressure. This may cause you to feel faint or dizzy. Inadequate fluid intake, excessive sweating, diarrhea, or vomiting can cause blood pressure to drop even more. Lie down if you feel faint or dizzy. Tell your healthcare provider if this happens.
High potassium levels. Your healthcare provider will monitor your potassium levels. Taking potassium supplements and foods containing high levels of potassium, including salt substitutes, may not be recommended. Ask your healthcare provider about taking potassium supplements and/or potassium-containing salt substitutes.
Liver failure. Your healthcare provider will monitor for liver problems. Tell your healthcare provider about any signs or symptoms of jaundice such as yellowing of your skin or the whites of your eyes.
Qbrelis can cause dizziness. Do not drive or operate heavy machinery until you know how Qbrelis affects you.
Do not take Qbrelis if you:
- are allergic to Qbrelis or to any of its ingredients
- have had an allergic reaction to another blood pressure medication that belongs to the same class (ACE inhibitor)
- have a history of hereditary or idiopathic angioedema
- have diabetes and are taking aliskiren
- are taking the medication Entresto
Qbrelis Food Interactions
Medications can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of Qbrelis, potassium supplements and foods containing high levels of potassium, including salt substitutes, may not be recommended. Ask your healthcare provider about taking potassium supplements and/or potassium-containing salt substitutes.
Before taking Qbrelis, tell your doctor about all of your medical conditions. Especially tell your doctor if you:
- are allergic to Qbrelis or any of its ingredients
- have or have had angioedema
- have a history of abnormal potassium levels
- are taking aliskiren
- are taking Entresto
- are pregnant or plan to become pregnant
- are breastfeeding or plan to breastfeed
Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements.
Qbrelis and Pregnancy
Tell your healthcare provider if you are pregnant or become pregnant.
Qbrelis can cause harm or death to your unborn baby. If you become pregnant, your doctor will have you stop taking Qbrelis as soon as possible.
Qbrelis and Lactation
Tell your healthcare provider if you are breastfeeding or plan to breastfeed.
There is no data available whether or not Qbrelis is present in human milk nor is data available on the effects of Qbrelis on the breastfed infant or on milk production. Qbrelis is present in rat milk.
Because of the potential for severe adverse reactions in the breastfed infant, it is not recommended to breastfeed during treatment with Qbrelis.
Take Qbrelis exactly as prescribed.
This medication comes in an oral solution to be taken by mouth once daily.
Take this medication exactly as prescribed by your doctor. Follow the directions on your prescription label carefully.
The dose your doctor recommends may be based on the following:
- the condition being treated
- other medical conditions you have
- other medications you are taking
- how you respond to this medication
- your weight
The recommended starting dose of Qbrelis for the treatment of hypertension in adults is 10mg. Then the dose can be increase to 40 mg based on you respond to the medication.
In children 6 years old and older, Qbrelis is dosed by weight at 0.07mg per kg and can be given up to 5mg daily.
The recommended starting dose of Qbrelis for the treatment of heart failure is 5mg and can be increased as tolerated up to 40mg daily.
The recommended dose for acute myocardial infarction (heart attack) is 5mg within 24 hours of the heart attack followed by 5mg after 24 hours, then 10mg once daily.
For those with whose kidneys do not work as well as they should, the dosing may be lowered.
If you take too much Qbrelis, call your healthcare provider or local Poison Control Center, or seek emergency medical attention right away.
Store Qbrelis at controlled room temperature: 68°F to 77°F (20°C to 25°C).
Keep this and all medicines out of the reach of children.
Qbrelis FDA Warning
Food and Drug Administration (FDA) Warning: FETAL TOXICITY
- When pregnancy is detected, discontinue Qbrelis as soon as possible
- Drugs that act directly on the renin-angiotensin system, like Qbrelis, can cause injury and death to the developing fetus