Purpose of NyQuil

NyQuil Cough is an over-the-counter medication used to temporarily treat cough, runny nose, and sneezing.

Active Ingredients

dextromethorphan 30 mg and doxylamine 12.5 mg in each 30 mL dose cup


Inactive Ingredients

alcohol, citric acid, FD&C blue #1, FD&C red #40, flavor, high fructose corn syrup, polyethylene glycol, propylene glycol, purified water, saccharin sodium, sodium citrate

NyQuil FDA Warning

Do not use:

  • if you are taking a monoamine oxidase inhibitor (MAOI), or for 2 weeks after stopping MAOI therapy
  • to make a child sleep
  • if you are unsure if your medication contains acetaminophen or MAOI, consult a physician or pharmacist before taking

Consult a physician before use if you have:

  • glaucoma
  • a cough that produces a lot of phlegm (mucus)
  • a breathing problem or chronic cough that occurs with smoking, asthma, or emphysema
  • trouble urinating due to enlarged prostate
  • a sodium-restricted diet

Consult a physician or pharmacist before use if you currently take sedatives or tranquilizers.

When using this product: 

  • do not use more than directed
  • excitability may occur, especially in children
  • it may cause drowsiness
  • do not drink alcohol
  • have caution when operating a motor vehicle or operating machinery
  • alcohol, sedatives and tranquilizers may increase drowsiness

Stop use and consult a physician if cough:

  • lasts more than a week
  • returns after treatment
  • occurs with fever, rash, or headache

If pregnant or breastfeeding, consult a physician before use.

Keep out of reach of children.

In case of an overdose, get medical help or contact a Poison Control Center right away (1-800-222-1222).

Tamper evident. Do not use if printed shrinkband is missing or broken.


  • Use dose cup or tablespoon (TBSP).
  • Do not exceed 4 doses per 24 hours.
  • For adults and children 12 years and over, take 30 mL (2 TBSP) every 6 hours.

Pediatric Use

  • Use dose cup or tablespoon (TBSP).
  • Do not exceed 4 doses per 24 hours.
  • For children 4 and under 12 years and over, ask a doctor before use.
  • For children under 4 years of age, do not use.

Other Information About NyQuil

  • Each 30 mL dose cup contains sodium 36 mg.
  • Store at room temperature.