Nurtec ODT

Nurtec ODT is used to treat and prevent migraine headaches. Talk to your doctor about eating grapefruit and drinking grapefruit juice while taking this medication.

Nurtec ODT Overview

Reviewed: December 1, 2021
Updated: 

Nurtec ODT is used to prevent and treat the symptoms of migraine headaches. Nurtec ODT belongs to a group of medications called calcitonin gene-related peptide receptor antagonists (CGRPs). It works by blocking the action of a certain natural substance in the body that causes migraine headaches.

Nurtec ODT comes as a tablet that is placed on or under the tongue where it dissolves without water. Nurtec ODT can be taken 1 time each day as needed for treatment of migraine headaches. You should not take more than 1 tablet in 24 hours. For the preventive treatment of episodic migraine, take Nurtec ODT once every other day. Up to 18 doses of Nurtec ODT can be taken per month.

Common side effects include nausea, stomach pain and indigestion.

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Nurtec ODT Cautionary Labels

precautionsprecautions

Uses of Nurtec ODT

Nurtec ODT is a prescription medicine used in adults for the:

  • acute treatment of migraine attacks with or without aura
  • preventive treatment of episodic migraine

It is not known if Nurtec ODT is safe and effective in children.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Rimegepant

For more information on this medication choose from the list of selections below.

Nurtec ODT Drug Class

Nurtec ODT is part of the drug class:

Side Effects of Nurtec ODT

Nurtec ODT may cause serious side effects. See "Drug Precautions" section.

The most common side effect of Nurtec ODT in acute treatment of migraine attacks with or without aura is nausea.

The most common side effects of Nurtec ODT in preventive treatment of episodic migraine are:

  • nausea
  • stomach pain
  • indigestion

These are not the only possible side effects of Nurtec ODT.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800 FDA-1088.

Nurtec ODT Interactions

Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements.

Especially tell your doctor if you take

  • antifungals such as fluconazole (Diflucan), itraconazole (Onmel, Sporanox, Tolsura), ketoconazole, and voriconazole (Vfend)
  • aprepitant (Emend)
  • clarithromycin 
  • ciprofloxacin (Cipro)
  • conivaptan (Vaprisol)
  • crizotinib (Xalkori)
  • cyclosporine (Gengraf, Neoral, Sandimmune)
  • diltiazem (Cardizem, Cartia, Taztia, Tiazac)
  • dronedarone (Multaq)
  • erythromycin (E.E.S., Eryc, Eryped, Ery-tab)
  • fluvoxamine (Luvox)
  • imatinib (Gleevac)
  • medications for human immunodeficiency virus (HIV) such as indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir, in Kaletra, in Viekira), and saquinavir (Invirase), tipranavir (Aptivus)
  • rifampin (Rifadin, Rimactane, in Rifamate, Rifater)
  • verapamil (Calan, Verelan, in Tarka)

This is not a complete list of Nurtec ODT drug interactions. Ask your doctor or pharmacist for more information.

Nurtec ODT Precautions

Nurtec ODT may cause serious side effects including:

  • Allergic reactions. Allergic reactions, including trouble breathing and rash, can happen after you take Nurtec ODT. This can happen days after you take Nurtec ODT. Call your healthcare provider or get emergency help right away if you have any of the following symptoms, which may be part of an allergic reaction:
    • Swelling of the face, mouth, tongue, or throat
    • Trouble breathing

Do not take Nurtec ODT if you are:

  • allergic to rimegepant, Nurtec ODT, or any of the ingredients in Nurtec ODT.

Nurtec ODT Food Interactions

Grapefruit and grapefruit juice may interact with this medication. Discuss the use of grapefruit products with your doctor.

Inform MD

Before you take Nurtec ODT, tell your healthcare provider about all of your medical conditions, including if you:

  • have liver problems.
  • have kidney problems.
  • are pregnant or plan to become pregnant. It is not known if Nurtec ODT will harm your unborn baby.
  • are breastfeeding or plan to breastfeed. It is not known if Nurtec ODT passes into your breast milk.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Nurtec ODT and Pregnancy

Tell your doctor if you are pregnant or plan to become pregnant. It is not known if Nurtec ODT will harm your unborn baby.

Nurtec ODT and Lactation

Tell your doctor if you are breastfeeding or plan to breastfeed. It is not known if Nurtec ODT passes into your breast milk.

Nurtec ODT Usage

  • Take Nurtec ODT exactly how your healthcare provider tells you to.
  • For the acute treatment of migraine attacks when they occur, Nurtec ODT can be taken 1 time each day as needed. You should not take more than 1 tablet in 24 hours.
    • It is not known if it is safe to take more than 18 doses of Nurtec ODT in 30 days.
  • For the preventive treatment of episodic migraine, take Nurtec ODT 1 time every other day.
  • To take Nurtec ODT:
    • Use dry hands when opening the blister pack.
    • Peel back the foil covering of one blister and gently remove Nurtec ODT. Do not push Nurtec ODT through the foil.
    • As soon as the blister is opened, remove Nurtec ODT and place on or under the tongue.
    • Nurtec ODT will dissolve and no drink or water is needed.
    • Take Nurtec ODT immediately after opening the blister pack. Do not store Nurtec ODT outside the blister pack for future use.
  • If you take too much Nurtec ODT, go to the nearest emergency room right away.

Nurtec ODT Overdose

If you take too much Nurtec ODT, call your local Poison Control Center or seek emergency medical attention right away.

Other Requirements

  • Store Nurtec ODT in the blister package that it comes in.
  • Store Nurtec ODT at room temperature between 68°F to 77°F (20°C to 25°C). 
  • Keep Nurtec ODT and all medicines out of the reach of children.