Fiasp

Fiasp is a man-made insulin used to control high blood sugar in adults with diabetes mellitus. Fiasp is similar to NovoLog but is formulated with other ingredients to increase the speed of absorption.

Fiasp Overview

Reviewed: November 20, 2017
Updated: 

Fiasp is a prescription medication used to treat type 1 and type 2 diabetes. Fiasp is a fast-acting insulin. It is usually given with long-acting insulin that provides a steady amount of insulin in the body to control blood glucose (sugar) levels. Insulin works by decreasing sugar in the blood and stopping the body from making more sugar.

This medication comes in an injectable form available in vials and prefilled pens. Fiasp should be injected just under the skin at the start of a meal or within 20 minutes after starting a meal. This medication is also available in an injectable form to be given directly into a vein (IV) by a healthcare professional.

Common side effects of Fiasp include low blood sugar, a reaction at the injection site, and weight gain. Fiasp can also cause blurred vision and dizziness. Do not drive or operate heavy machinery until you know how Fiasp affects you.

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Fiasp Cautionary Labels

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Uses of Fiasp

Fiasp is a man-made insulin used to control high blood sugar in adults with diabetes mellitus. It is not known if Fiasp is safe and effective in children.

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

Fiasp Drug Class

Fiasp is part of the drug class:

Side Effects of Fiasp

Serious side effects have been reported with Fiasp. See the “Fiasp Precautions” section.

Common side effects of Fiasp include:

  • skin problems such as eczema, rash, itching, redness and swelling of your skin (dermatitis)
  • reactions at the injection site such as itching, rash, skin thickening or pits at the injection site (lipodystrophy)
  • weight gain

Low blood sugar, or hypoglycemia, is the most common side effect seen with Fiasp use. Symptoms of low blood sugar include:

  • sweating
  • dizziness or lightheadedness
  • blurred vision
  • anxiety, irritability, or other mood changes
  • shakiness
  • slurred speech
  • hunger
  • confusion
  • headache
  • fast heart beat

Severe low blood sugar can cause fainting or passing out, seizures, and even death. Know your symptoms of low blood sugar and follow your healthcare provider's instructions for treating low blood sugar. 

This is not a complete list of Fiasp side effects. Ask your doctor or pharmacist for more information. Tell your doctor if you have any side effects that bother you or that do not go away. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Fiasp Interactions

Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your doctor if you take:

  • oral medications for diabetes, pramlintide, some blood pressure medications like ACE inhibitors, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, propoxyphene, salicylates, somatostatin analogs, and sulfonamide antibiotics. These medicines may increase the blood-glucose-lowering effect and susceptibility to hypoglycemia (low blood sugar).
  • corticosteroids, niacin, danazol, diuretics, sympathomimetic agents (e.g., epinephrine, salbutamol, terbutaline), isoniazid, phenothiazine derivatives, somatropin, thyroid hormones, estrogens, progestogens (e.g., in oral contraceptives), and atypical antipsychotics (olanzapine and clozapine). These medicines may reduce the blood-glucose-lowering effect.
  • beta-blockers, clonidine, lithium salts, and alcohol. These may either potentiate or weaken the blood-glucose-lowering effect of insulin.
  • beta-blockers, clonidine, guanethidine, and reserpine. These medicines may reduce the signs of hypoglycemia (low blood sugar).

This is not a complete list of Fiasp drug interactions. Ask your doctor or pharmacist for more information.

Fiasp Precautions

Serious side effects have been reported with Fiasp including the following:

  • hypersensitivity (severe allergic reaction). Tell your healthcare provider about any signs or symptoms of hypersensitivity including chest pain, swelling of the face or mouth, difficulty breathing or swallowing, or rash.
  • reactions at the injection site (local allergic reaction). You may get redness, swelling, and itching at the injection site. If you keep having skin reactions, talk to your healthcare provider. You may need to stop using Fiasp and use a different insulin. Do not inject Fiasp into skin that is red, swollen, or itchy.
  • skin thickens or pits at the injection site (lipodystrophy). Change (rotate) where you inject your insulin to help to prevent these skin changes from happening. Do not inject insulin into this type of skin.
  • low blood sugar (hypoglycemia). Monitor yourself for signs and symptoms of low blood sugar and follow you low blood sugar plant or tell your healthcare provider. Symptoms include hunger, shakiness, dizziness, confusion, difficulty speaking, feeling anxious or weak, vision changes.
  • low potassium in your blood (hypokalemia).

Fiasp can cause dizziness and blurred vision. Do not drive or operate heavy machinery until you know how Fiasp affects you. You may have difficulty concentrating or reacting if you have low blood sugar (hypoglycemia). Ask your doctor if it is alright to drive if you often have low blood sugar or decrease to no warning signs of low blood sugar.

While using Fiasp, avoid alcohol. Alcohol, including beer and wine, may affect your blood sugar when you take Fiasp.

Do not take Fiasp if:

  • your blood sugar is too low (hypoglycemia).
  • you are allergic to anything in Fiasp. Check with your doctor if you are not sure.

Fiasp Food Interactions

Follow dietary (food) recommendations made by your doctor and dietitian which should include a healthy diet. Skipping meals should be avoided as this can cause problems maintaining blood sugar control. There are no specific foods to avoid while using Fiasp.

Inform MD

Before taking Fiasp, tell your doctor about all of your medical conditions. Especially tell your doctor if you:

  • are allergic to Fiasp or to any of its ingredients
  • have liver problems
  • have kidney problems
  • are pregnant or plan to become pregnant
  • are breastfeeding or plan to breastfeed

Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements.

Fiasp and Pregnancy

Tell your doctor if you are pregnant or plan to become pregnant.

In animal studies, pregnant animals were given this medication and had some babies born with problems. No well-controlled studies have been done in humans.

It is important to maintain control of your blood sugar levels during pregnancy. Therefore, this medication may be used if the potential benefits to the mother outweigh the potential risks to the unborn child. Your doctor will decide which insulin is best for you during your pregnancy.

Fiasp and Lactation

Tell your doctor if you are breastfeeding or plan to breastfeed.

It is not known if Fiasp crosses into human milk. Because many medications can cross into human milk and because of the possibility for serious adverse reactions in nursing infants with use of this medication, a choice should be made whether to stop nursing or stop the use of this medication. Your doctor and you will decide if the benefits outweigh the risk of using Fiasp.

Fiasp Usage

This medication comes in an injectable form available in vials and prefilled pens. Fiasp should be injected just under the skin at the start of a meal or within 20 minutes after starting a meal. This medication is also available in an injectable form to be given directly into a vein (IV) by a healthcare professional.

Read the instructions for use that come with your Fiasp product. Talk to your doctor if you have any questions. Your doctor should show you how to inject Fiasp before you start taking it.

  • Take Fiasp exactly as prescribed. You should eat a meal immediately or within 20 minutes after using Fiasp to avoid low blood sugar.
  • Fiasp is a fast-acting insulin. The effects of Fiasp start working in 15-20 minutes after injection.
  • Do not inject Fiasp if you do not plan to eat right after your injection.
  • While using Fiasp you may have to change your total dose of insulin, your dose of longer-acting insulin, or the number of injections of longer-acting insulin you use.
  • Inject Fiasp into the skin of your stomach area, upper arms, buttocks or upper legs. Fiasp may affect your blood sugar levels sooner if you inject it into the skin of your stomach area. Never inject Fiasp into a vein or into a muscle.
  • Change (rotate) your injection site within the chosen area (for example, stomach or upper arm) with each dose. Do not inject into the exact same spot for each injection.
  • Only use Fiasp if it appears clear and colorless. There may be air bubbles. This is normal. If it looks cloudy, thickened, or colored, or if it contains solid particles do not use it.
  • Do not mix Fiasp with any insulins other than NPH when used with injections by syringe

If you take too much Fiasp, your blood sugar may fall low (hypoglycemia). You can treat mild low blood sugar (hypoglycemia) by drinking or eating something sugary right away (fruit juice, sugar candies, or glucose tablets). It is important to treat low blood sugar (hypoglycemia) right away because it could get worse and you could pass out (become unconscious). If you pass out you will need help from another person or emergency medical services right away, and will need treatment with a glucagon injection or treatment at a hospital.


If you forget to take your dose of Fiasp, your blood sugar may go too high (hyperglycemia). If high blood sugar (hyperglycemia) is not treated it can lead to serious problems, like loss of consciousness (passing out), coma or even death. Follow your doctor’s instructions for treating high blood sugar.

Fiasp Dosage

Take Fiasp exactly as prescribed by your doctor. Follow the directions on your prescription label carefully.

Your doctor will determine the best dose for you. The dosage of Fiasp is individualized.

Fiasp Overdose

If you take too much Fiasp, your blood sugar may fall low (hypoglycemia). You can treat mild low blood sugar by drinking or eating something sugary right away (fruit juice, sugar candies, or glucose tablets). Check your blood sugar if you think it is low.

If you take too much Fiasp, you can call your healthcare provider or local Poison Control Center, or seek emergency medical attention right away. 

It is important to treat low blood sugar right away because it could get worse and you could pass out. If you pass out, you will need help from another person or emergency medical services right away and will need treatment with a glucagon injection or treatment at a hospital.

Other Requirements

Keep this and all medicines out of the reach of children.

All unopened Fiasp:

  • Keep all unopened Fiasp in the refrigerator between 36° to 46°F (2° to 8°C).
  • Do not freeze. Do not use Fiasp if it has been frozen.
  • Keep unopened Fiasp in the carton to protect from light.
  • Unopened Fiasp can be used until the expiration date on the label, if the medicine has been stored in a refrigerator.

Fiasp in use or opened:

Vials

  • Keep in the refrigerator or at room temperature below 86°F (30°C) for up to 28 days.
  • Keep vials away from direct heat or light.
  • Throw away an opened vial after 28 days of use, even if there is Fiasp left in the vial.
  • Do not draw up Fiasp into a syringe and store for later use.

Fiasp FlexTouch

  • Keep at room temperature below 86°F (30°C) for up to 28 days.
  • Keep Fiasp FlexTouch away from direct heat or light.
  • Throw away a used Fiasp FlexTouch after 28 days, even if there is insulin left in the cartridge or syringe.
  • Always remove the needle after injection and place cap back on the Fiasp FlexTouch pen to protect from light and prevent contamination.