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Droxidopa Overview

Reviewed: February 19, 2014

Droxidopa is a prescription medication used in the treatment of orthostatic dizziness, lightheadedness, or the “feeling that you are about to black out” in adult patients with symptomatic NOH caused by primary autonomic failure (Parkinson’s disease, multiple system atrophy and pure autonomic failure), dopamine beta hydroxylase deficiency and non-diabetic autonomic neuropathy.

Droxidopa comes in capsule form and is taken three times daily. Swallow droxidopa capsules whole.

Common side effects include headache, dizziness, nausea, high blood pressure (hypertension) and fatigue.


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Uses of Droxidopa

Droxidopa is a prescription medication approved for the treatment of orthostatic dizziness, lightheadedness, or the “feeling that you are 
about to black out” in adult patients with symptomatic neurogenic orthostatic hypotension (NOH) caused by primary autonomic failure [Parkinson's disease (PD), multiple system atrophy and pure autonomic failure], dopamine beta-hydroxylase deficiency, and non-diabetic autonomic neuropathy. 
This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

Droxidopa Drug Class

Droxidopa is part of the drug class:

Side Effects of Droxidopa

Common side effects include:


Droxidopa Usage

Droxidopa Overdose

If you take too much droxidopa, call your local Poison Control Center or seek emergency medical attention right away.

Droxidopa FDA Warning

Warning: Healthcare professionals and patients should be warned of the risk of increased blood pressure while lying down (supine hypertension), a common problem that affects people with primary autonomic failure and can cause stroke. It is essential that patients be reminded that they must sleep with their head and upper body elevated. Supine blood pressure should be monitored prior to and during treatment and more frequently when increasing doses.

If supine hypertension cannot be managed by elevation of the head of the bed, reduce or discontinue droxidopa.

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