Degarelix treats prostate cancer. May cause hot flashes. It is injected under the skin in the stomach area.
Degarelix is a prescription medication used to treat advanced prostate cancer. Degarelix belongs to a group of drugs called gonadotropin-releasing hormone (GnRH) blockers. It works by reducing the amount of testosterone in the body, which prostate cancer cells need to grow.
This medication comes in an injectable form to be injected under the skin in the area of the stomach once every 28 days.
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Degarelix Cautionary Labels
Uses of Degarelix
Degarelix is a prescription medication used in the treatment of advanced prostate cancer.
This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.
Degarelix Brand Names
Degarelix may be found in some form under the following brand names:
Degarelix Drug Class
Degarelix is part of the drug class:
Side Effects of Degarelix
The common side effects include:
- hot flashes
- injection site pain, redness, and swelling, especially with the first dose
- weight gain
- increase in some liver enzymes
- back and joint pain
- urinary tract infection
- decreased sex drive and trouble with erectile function (impotence)
Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your doctor if you take medicines for your heart. Degarelix can cause a change in the heart rhythm known as QT prolongation. Be sure to mention any of the following medicines:
- amiodarone (Cordarone)
- disopyramide (Norpace)
This is not a complete list of degarelix drug interactions. Ask your doctor or pharmacist for more information.
Degarelix can cause a serious heart rhythm problem known as QT prolongation. Tell your doctor if you have heart disease.
You should not receive degarelix if you are allergic to any ingredient in degarelix. Signs of an allergic reaction are:
- Unexplained swelling of the mouth or throat
- Difficulty breathing or swallowing
Degarelix Food Interactions
Medicines can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of degarelix there are no specific foods that you must exclude from your diet when receiving degarelix.
Before receiving degarelix, tell your doctor about all your medical conditions, including if you:
- have any heart problems
- have problems with balance of your body salts or electrolytes, such as sodium, potassium, calcium, and magnesium
- have kidney or liver problems
- are pregnant or plan to become pregnant
- are breastfeeding or plan to breastfeed
- have any allergies to medications, foods, dyes, or perservatives
Tell your doctor about all the medicines you take, including prescription and nonprescription medicines, vitamins, and herbal supplements.
Degarelix and Pregnancy
Tell your doctor if you are pregnant or plan to become pregnant. The FDA categorizes medications based on safety for use during pregnancy. Five categories - A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy. This medication falls into category X.
This medication is not intended for use in women and should especially be avoided by pregnant women. Tell your doctor if you are pregnant or plan to become pregnant. Women who are pregnant or may become pregnant should not receive degarelix. This medication may harm the unborn baby.
Degarelix and Lactation
Tell your doctor if you are breastfeeding or plan to breastfeed. It is not known if degarelix is excreted in human breast milk or if it will harm your nursing baby.
Degarelix comes as a liquid to be injected under the skin (subcutaneously) of the stomach area, usually once every 28 days. The area where the medication is injection should change with each dosage. It should not be injected in the area of the ribs or waistline as these areas could be easily rubbed against or receive pressure.
This medication is usually given by a doctor or nurse in a medical facility, such as the doctor's office, clinic, or hospital.
- The injected medicine gives you a continuous release of degarelix over one month.
- Two injections are given as a first dose and the following monthly doses are one injection.
- Always set up an appointment for your next injection.
- If you miss a dose of degarelix, or if you think you forgot to get your monthly dose of degarelix, talk to your healthcare provider about how to get your next dose.
Take this medication exactly as prescribed by your doctor. Follow the directions on your prescription label carefully. The dose your doctor recommends may be based on the following:
- the condition being treated
- other medical conditions you have
- other medications you are taking
- how you respond to this medication
- your weight
- your height
- your age
- your gender
The starting dose of degarelix is two 120 mg injections (240 mg) on the first day of treatment. The mainanence dose of one 80 mg injection is given 28 days after the first dose. The 80 mg maintenance dose will be given every 28 days until treatment ends.
Degarelix is usually administered by a healthcare provider in a medical setting making it unlikely for an overdose to occur. However, if overdose is suspected, seek emergency medical attention.
Keep all medical and laboratory appointments while receiving this medication. To get the most benefit from this medication you should not skip doses. If you are unable to make an appointment, reschedule as soon as possible.