Clarinex-D 24 Hour

The RxWiki Digital Pharmacist stamp of approval lets you know that this content has been created and reviewed by a licensed pharmacist.

Clarinex-D 24 Hour Overview

Reviewed: September 12, 2012
Updated: March 1, 2013

Clarinex-D 24 Hour (generic: desloratadine/pseudoephedrine) is a prescription medication used to treat the symptoms of seasonal allergies (sneezing, itching, runny nose, and watery eyes) and nasal congestion.

Clarinex-D 24 Hour is a single tablet that contains 2 medications, desloratadine and pseudoephedrine. Desloratadine is an antihistamine that inhibits histamine release from human mast cells to help relieve sneezing, itching, runny nose, and watery eyes. Pseudoephedrine is a decongestant that shrinks the blood vessels in the nose which results in reduced swelling and mucus formation in the nasal passages to help relieve nasal congestion (stuffy nose).

Clarinex-D 24 Hour comes in tablet form and is taken once a day, with or without food. 
 
Some of the common side effects of Clarinex-D 24 Hour include headache, dizziness, dry mouth, and difficulty sleeping. 

Uses of Clarinex-D 24 Hour

Clarinex-D 24 Hour is a prescription medicine used to treat the symptoms of seasonal allergic rhinitis (sneezing, stuffy nose, runny nose and itching of the nose) in patients 12 years and older. 

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

 

Side Effects of Clarinex-D 24 Hour

Clarinex-D 24 Hour Extended Release Tablets may cause serious side effects, including:

  • Cardiovascular and central nervous system effects, such as
    • unable to sleep (insomnia)
    • dizziness
    • weakness
    • tremor
    • irregular heart beat
    • seizure
    • low blood pressure
  • Increased sleepiness or tiredness can happen if you take more Clarinex-D 24 Hour Extended Release Tablets than your doctor prescribed to you.
  • Allergic reactions. Stop taking Clarinex-D 24 Hour Extended Release Tablets and call your doctor right away or get emergency help if you have any of these symptoms:
    • rash
    • itching
    • hives
    • swelling of your lips, tongue, face, and throat
    • shortness of breath or trouble breathing

The most common side effects of Clarinex-D 24 Hour Extended Release Tablets include:

  • dry mouth
  • headache
  • unable to sleep (insomnia)
  • tiredness
  • sore throat
  • sleepiness
  • nausea
  • dizziness
  • nervousness
  • restlessness
  • poor appetite

Tell your doctor if you have any side effect that bothers you or that does not go away.

These are not all of the possible side effects of Clarinex-D 24 Hour Extended Release Tablets. For more information, ask your doctor or pharmacist.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Clarinex-D 24 Hour Interactions

Tell your doctor about all the medicines your take, including prescription and non-prescription medicines, vitamins and herbal supplements. Clarinex-D 24 Hour Extended Release Tablets may affect the way other medicines work, and other medicines may affect how Clarinex-D 24 Hour Extended Release Tablets works. Especially tell your doctor if you take:

  • Monoamine Oxidase Inhibitors (MAOI). You should not use Clarinex-D 24 Hour Extended Release Tablets if you take a MAOI or within 2 weeks of stopping an MAOI.
  • methyldopa
  • reserpine (Serpalan)
  • digitalis (Digoxin, Lanoxicaps, Lanoxin)
  • ketoconazole (Nizoral)
  • erythromycin (Ery-tab, Eryc, PCE)
  • azithromycin (Zithromax, Zmax)
  • antihistamines
  • other decongestant medicines

Know the medicines you take. Keep a list of your medicines and show it to your doctor and pharmacist when you get a new medicine.

 

Clarinex-D 24 Hour Precautions

Do not take Clarinex-D 24 Hour Extended Release Tablets if you:

  • are allergic to desloratadine or pseudoephedrine sulfate or any of the ingredients in Clarinex-D 24 Hour Extended Release Tablets. 
  • are allergic to loratadine (Alavert, Claritin)
  • have narrow angle glaucoma
  • have problems with urination (urinary retention)
  • take a Monoamine Oxidase Inhibitor (MAOI) medicine to treat depression, or if you stopped taking an MAOI medicine within the last 2 weeks. Ask your doctor or pharmacist if you are not sure if you take an MAOI medicine.
  • have severe high blood pressure
  • have severe heart disease

Talk to your doctor before taking this medicine if you have any of these conditions.

 

Inform MD

Before you take Clarinex-D 24 Hour Extended Release Tablets, tell your doctor if you:

  • have any of the conditions listed in the section "Drug Precautions".
  • diabetes
  • hyperthyroidism
  • have prostate problems
  • have liver or kidney problems
  • have any other medical conditions
  • are pregnant or plan to become pregnant. It is not known if Clarinex-D 24 Hour Extended Release Tablets will harm your unborn baby. Talk to your doctor if you are pregnant or plan to become pregnant.
  • are breastfeeding or plan to breastfeed. Clarinex-D 24 Hour Extended Release Tablets can pass into your breast milk. Talk to your doctor about the best way to feed your baby if you take Clarinex-D 24 Hour Extended Release Tablets.

Tell your doctor about all the medicines your take, including prescription and non-prescription medicines, vitamins and herbal supplements.

Clarinex-D 24 Hour and Pregnancy

Tell your doctor if you are pregnant or plan to become pregnant. It is not known if Clarinex-D 24 Hour Extended Release Tablets will harm your unborn baby. Talk to your doctor if you are pregnant or plan to become pregnant.

Clarinex-D 24 Hour and Lactation

Tell your doctor if you are breastfeeding or plan to breastfeed. Clarinex-D 24 Hour Extended Release Tablets can pass into your breast milk. Talk to your doctor about the best way to feed your baby if you take Clarinex-D 24 Hour Extended Release Tablets.

Clarinex-D 24 Hour Usage

  • Take Clarinex-D 24 Hour Extended Release Tablets exactly as your doctor tells you to take it.
  • Clarinex-D 24 Hour Extended Release Tablets can be taken with or without food.
  • Swallow Clarinex-D 24 Hour Extended Release Tablets whole. Do not break, crush, or chew Clarinex-D 24 Hour Extended Release Tablets before swallowing. If you can not swallow Clarinex-D 24 Hour Extended Release Tablets whole, tell your doctor. You may need a different medicine.
  • Take 1 Clarinex-D 24 Hour Extended Release Tablets every day.

Forms of Clarinex-D 24 Hour

Active ingredients: desloratadine and pseudoephedrine sulfate

Inactive ingredients: hypromellose USP, ethylcellulose NF, dibasic calcium phosphate dihydrate USP, magnesium stearate NF, povidone USP, silicone dioxide NF, talc USP, polyacrylate dispersion, polyethylene glycol NF, simethicone USP, Blue Lake Blend 50726 (FD&C Blue No. 2 Lake, titanium dioxide USP and edetate disodium USP), and ink (Opacode S-1-17746 or Opacode S-1-4159).

Other Requirements

  • Store Clarinex-D 24 Hour Extended Release Tablets at 59˚F to 86˚F (15˚C to 30˚C)
  • Keep Clarinex-D 24 Hour Extended Release Tablets dry and out of the light.

Keep Clarinex-D 24 Hour Extended Release Tablets and all medicines out of the reach of children.

Reviewed:  September 12, 2012
Updated:  March 1, 2013

Sign up for

My RxWiki  &   RxWiki Notify

Follow the medications that matter most to
you and Ask related questions.

Receive email notifications as soon as your
medication pages are updated.