Auryxia

Auryxia controls serum phosphorous levels and treats iron deficiency anemia. Since Auryxia contains iron, it may cause discolored (dark) stools.

Auryxia Overview

Reviewed: January 15, 2015
Updated: 

Auryxia is a prescription medication used to control serum phosphorus levels in patients with chronic kidney disease (CKD) on dialysis. It is also used to treat iron deficiency anemia in patients with chronic kidney disease (CKD) not on dialysis.

Auryxia belongs to a group of drugs called ferric iron-based phosphate binders. These work by binding to phosphate in the body to pass it through the digestive system and eliminate the phosphate through the stool. In addition, Auryxia can help replenish iron in the body necessary to make red blood cells.  

This medication comes in tablet form and is taken typically 3 times a day, with meals.

Common side effects of Auryxia include diarrhea, discolored (dark) stools, nausea, constipation, and vomiting.

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Auryxia Cautionary Labels

precautionsprecautionsprecautions

Uses of Auryxia

Auryxia is a prescription medication used to:

  • control serum phosphorous levels in patients with chronic kidney disease (CKD) on dialysis
  • treat iron deficiency anemia in patients with chronic kidney disease (CKD) not on dialysis.

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

Manufacturer

Auryxia Drug Class

Auryxia is part of the drug class:

Side Effects of Auryxia

Serious side effects have been reported with Auryxia. See the “Auryxia Precautions” section.

Common side effects of Auryxia include the following:

  • discolored feces 
  • diarrhea
  • constipation 
  • nausea
  • vomiting
  • cough
  • abdominal pain
  • and hyperkalemia (high potassium levels in your blood)

This is not a complete list of Auryxia side effects. Ask your doctor or pharmacist for more information.

Tell your doctor if you have any side effects that bother you or that do not go away.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Auryxia Interactions

Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your doctor if you take antibiotic medications such as doxycycline or ciprofloxacin

This is not a complete list of Auryxia drug interactions. Ask your doctor or pharmacist for more information.

Auryxia Precautions

There is a risk of overdosage in children due to accidental ingestion. Accidental ingestion and resulting overdose of iron-containing products is a leading cause of fatal poisoning in children under 6 years of age. Keep Auryxia out of the reach of children.

Auryxia Food Interactions

Medications can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of Auryxia, there are no specific foods that you must exclude from your diet when receiving this medication.

Inform MD

Before taking Auryxia, tell your doctor about all of your medical conditions. Especially tell your doctor if you:

  • are allergic to Auryxia or to any of its ingredients
  • are pregnant or plan to become pregnant
  • are breastfeeding or plan to breastfeed

Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements.

Auryxia and Pregnancy

Tell your doctor if you are pregnant or plan to become pregnant.

No studies have been done in animals, and no well-controlled studies have been done in pregnant women. Auryxia should be given to a pregnant woman only if clearly needed.

Auryxia and Lactation

Tell your doctor if you are breastfeeding or plan to breastfeed.

It is not known if Auryxia crosses into human milk. Because many medications can cross into human milk and because of the possibility for serious adverse reactions in nursing infants with use of this medication, a choice should be made whether to stop nursing or stop the use of this medication. Your doctor and you will decide if the benefits outweigh the risk of using Auryxia.

Auryxia Usage

Take Auryxia exactly as prescribed.

Auryxia comes in tablet form and is taken three times every day with meals. 

Take with food.

If you miss a dose, take the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and take your next dose at the regular time. Do not take two doses of Auryxia at the same time.

Auryxia Dosage

Take this medication exactly as prescribed by your doctor. Follow the directions on your prescription label carefully.

The dose your doctor recommends may be based on the following:

  • the condition being treated
  • other medical conditions you have
  • other medications you are taking
  • how you respond to this medication

The recommended starting dose of Auryxia for the control of serum phosphorus levels in patients with chronic kidney disease on dialysis is 2 tablets orally 3 times per day with meals. The dose can be adjusted by 1 to 2 tablets as needed to maintain serum phosphorus at target levels, up to a maximum of 12 tablets daily.

The recommended starting dose of Auryxia for the treatment of iron deficiency anemia in patients with chronic kidney disease (CKD) not on dialysis is 1 tablet orally 3 times per day with meals. The dose can be adjusted as needed to achieve and maintain hemoglobin goal, up to a maximum of 12 tablets daily. 

Auryxia Overdose

If you take too much Auryxia, call your healthcare provider or local Poison Control Center, or seek emergency medical attention right away.

Other Requirements

  • Store Auryxia at room temperature (20 to 25°C (68 to 77°F). 
  • Keep this and all medicines out of the reach of children.