Admelog

Admelog is a rapid-acting, man-made insulin used to treat diabetes. Admelog comes in a vial or in a SoloStar disposable, prefilled pen.

Admelog Overview

Reviewed: January 11, 2018
Updated: 

Admelog is a prescription medication to treat type 1 and type 2 diabetes for patients 3 years and older. Admelog is a rapid-acting form of insulin that is given with a meal.

Insulin is naturally produced by the body to control the amount of sugar (glucose) in the blood. In patients with type 1 diabetes, the body does not make insulin and must be replaced by injections of insulin. In patients with type 2 diabetes, the body makes insulin but does not use it efficiently or appropriately.

This medication comes in an injectable form available in vials and prefilled pens. Admelog should be injected just under the skin 15 minutes before a meal or immediately after a meal. It may also be injected by an insulin pump or directly into a vein (IV) by a healthcare provider.

Common side effects of Admelog include low blood sugar (hypoglycemia) and allergic reaction. Admelog can also cause drowsiness and dizziness. Do not drive or operate heavy machinery until you know how Admelog affects you.

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  • Other
  • Diabetes Mellitus, Type 1
  • Diabetes Mellitus, Type 2
  • Hyperglycemia

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Admelog Cautionary Labels

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Uses of Admelog

Admelog is a man-made insulin used to control high blood sugar in adults and children with diabetes mellitus.

  • It is not known if Admelog is safe and effective in children younger than 3 years of age or when used to treat children with type 2 diabetes mellitus. 

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

Admelog Drug Class

Admelog is part of the drug class:

Side Effects of Admelog

Serious side effects have been reported with Admelog. See the “Admelog Precautions” section.

Common side effects of Admelog include the following:

  • low blood sugar (hypoglycemia)
  • allergic reactions
  • reaction at the injection site
  • changes in the feel of your skin such as skin thickening or a little indentation in the skin (lipodystrophy)
  • itching
  • rash

This is not a complete list of Admelog side effects. Ask your doctor or pharmacist for more information.

Tell your doctor if you have any side effects that bother you or that do not go away.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Admelog Interactions

Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your doctor if you take:

  • any oral antidiabetic agents such as glyburide, metformin, glipizide, sitagliptin, pioglitazone, saxagliptin, dapagliflozin, linagliptin, and pioglitazone
  • beta blockers such as metoprolol, carvedilol, bisoprolol, betaxolol, nebivolol, and propranolol 
  • clonidine
  • lithium
  • reserpine
  • any hormone products including estrogens or progesterones like birth control
  • any thyroid medications such as levothyroxine, Synthroid, and Levothroid
  • any corticosteroids like dexamethasone
  • any  angiotensin-converting enzyme (ACE) blockers for high blood pressure such as benazepril, captopril, enalapril, fosinopril, lisinopril, moexipril, quinapril, ramipril, and trandolapril
  • diuretics such as acetazolamide, amiloride, bumetanide, chlorothiazide, chlorthalidone, ethacrynic acid, furosemide, hydrochlorothiazide, metolazone, torsemide, and triamterene
  • monoamine oxidase inhibitors such as isocarboxazid, phenelzine, tranylcypromine, selegiline, and rasagiline
  • salicylate pain relievers such as aspirin, choline magnesium trisalicylate (Trisalate), choline salicylate (Arthropan), diflunisal (Dolobid), magnesium salicylate (Doan's, others), and salsalate (Argesic, Disalcid, Salgesic)
  • octreotide (Sandostatin)
  • epinephrine
  • albuterol
  • terbutaline
  • pramlintide
  • fluoxetine
  • propoxyphene
  • danazol
  • isoniazid
  • somatropin
  • certain cholesterol-lowering medications such as fenofibrate (Antara, Lofibra, TriCor, Triglide), gemfibrozil (Lopid), and niacin (Niacor, Niaspan, in Advicor)
  • sulfonamide antibiotics such as trimethoprim-sulfamethoxazole (Bactrim)
  • disopyramide
  • phenothiazine derivatives such as prochlorperazine, chlorpromazine, fluphenazine, perphenazine, trifluoperazine, and thioridazine
  • atypical antipsychotics such as risperidone, olanzapine, quetiapine, aripiprazole, lurasidone, paliperidone

This is not a complete list of Admelog drug interactions. Ask your doctor or pharmacist for more information.

Admelog Precautions

Serious side effects have been reported with Admelog including the following:

  • low blood sugar (hypoglycemia). Low blood sugar can occur with changes in insulin regimens or dose miscalculations. Monitor blood sugar levels regularly. Signs and symptoms of low blood sugar include sweating, dizziness or lightheadedness, shakiness, hunger, fast heartbeat, trouble concentrating or confusion, blurred vision, slurred speech, anxiety, irritability or mood changes, and headache
  • hypersensitivity (severe allergic reaction). Tell your healthcare provider about any signs or symptoms of hypersensitivity, including rash, chest pain, difficulty breathing or swallowing, or swelling of the face, eyes, lips, tongue, arms, or leg
  • low potassium in your blood (hypokalemia).
  • fluid retention and heart failure can occur with use of Admelog with thiazolidinediones (TZDs)

Admelog can cause drowsiness and dizziness. Do not drive or operate heavy machinery until you know how Admelog affects you. Ask your doctor if it is alright to drive if you often have low blood sugar or decreased or no warning signs of low blood sugar.

While using Admelog avoid:

  • Alcohol. Alcohol, including beer and wine, may affect your blood sugar when you take Admelog.
  • Driving and operating machinery. You may have difficulty concentrating or reacting if you have low blood sugar (hypoglycemia). Be careful when you drive a car or operate machinery.  

Do not take Admelog if: 

  • you are allergic to Admelog or to any of its ingredients
  • your blood sugar is too low (hypoglycemia)

Admelog Food Interactions

Medications can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of Admelog, there are no specific foods that you must exclude from your diet when receiving this medication.

Inform MD

Before taking Admelog, tell your doctor about all of your medical conditions. Especially tell your doctor if you:

  • are allergic to Admelog or to any of its ingredients
  • have heart failure or other heart problems
  • have liver problems
  • have kidney problems
  • are pregnant or plan to become pregnant
  • are breastfeeding or plan to breastfeed

Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements.

Admelog and Pregnancy

Tell your doctor if you are pregnant or plan to become pregnant.

There are no well-done studies that have been done in humans with Admelog. In animal studies, pregnant animals were given a closely related medication, and the babies did not show any medical issues related to this medication.

Admelog and Lactation

Tell your doctor if you are breastfeeding or plan to breastfeed.

It is not known if Admelog crosses into human milk. Because many medications can cross into human milk and because of the possibility for serious adverse reactions in nursing infants with use of this medication, a choice should be made whether to stop nursing or stop the use of this medication. Your doctor and you will decide if the benefits outweigh the risk of using Admelog.

Admelog Usage

Read the instructions for use that come with your Admelog product. Talk to your doctor if you have any questions. Your doctor should show you how to inject Admelog before you start taking it.

  • Take Admelog exactly as prescribed. You should eat a meal within 15 minutes before a meal or immediately after a meal.
  • Change (rotate) your injection site within the chosen area (for example, stomach or upper arm) with each dose. Do not inject into the exact same spot as the last injection.
  • Do not inject Admelog if you do not plan to eat right after your injection or bolus pump infusion.
  • Do not mix Admelog with any other insulins.

If you miss a dose and remember it before or shortly after your meal, inject the missed dose right away. If some time has passed since your meal, follow the instructions provided by your doctor or call your doctor to find out whether you should inject the missed dose. Do not inject a double dose to make up for a missed one.

Admelog Dosage

Take this medication exactly as prescribed by your doctor. Follow the directions on your prescription label carefully.

The dosage of Admelog is individualized. Your healthcare provider will determine the correct dose for you. 

Admelog Overdose

If you take too much Admelog, your blood sugar may fall low (hypoglycemia). You can treat mild low blood sugar (hypoglycemia) by drinking or eating something sugary right away (fruit juice, sugar candies, or glucose tablets). It is important to treat low blood sugar (hypoglycemia) right away because it could get worse and you could pass out (become unconscious). Call your healthcare provider or local Poison Control Center or seek emergency medical attention right away if you take too much Admelog.

Other Requirements

Do not reuse or share needles or syringes.

Unopened Admelog vials and Admelog Solostar prefilled pens

  • Store in the refrigerator between 36° to 46°F (2° to 8°C).
  • Do not freeze.

Opened Admelog vials

  • Store at room temperature below 86°F (30°C) or in the refrigerator between 36° to 46°F (2° to 8°C).
  • Throw away an opened vial after 28 days of use, even if there is Admelog left in the vial.
  • Store in the container to protect Admelog from light

Opened Admelog Solostar prefilled pens

  • Store at room temperature below 86°F (30°C).
  • Do not refrigerate opened Admelog Solostar prefilled pens.
  • Throw away an opened vial after 28 days of use, even if there is Admelog left in the vial.
  • Store in the container to protect Admelog from light