Remeron

Remeron treats depression. Can cause weight gain and drowsiness.

Remeron Overview

Reviewed: September 14, 2012
Updated: 

Remeron is a prescription medication used to treat depression. Remeron belongs to a group of drugs called antidepressants, which may help maintain mental balance by blocking certain receptors in the brain.

This medication comes as a regular tablet and is taken once a day in the evening, with or without food.   

Common side effects of Remeron include increased appetite, dry mouth, and constipation.

Remeron can cause drowsiness and dizziness. Do not drive or operate machinery until you know how this medication will affect you. 

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Remeron Cautionary Labels

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Uses of Remeron

Remeron is a prescription medicine used to treat depression. 

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

Manufacturer

Remeron Drug Class

Remeron is part of the drug class:

Side Effects of Remeron

Remeron may cause serious side effects, including all of those described in the section entitled "Drug Precautions".

Common possible side effects in people who take Remeron include:

  • sleepiness
  • increased appetite, weight gain
  • dry mouth
  • constipation
  • dizziness
  • abnormal dreams

Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of Remeron. For more information, ask your healthcare provider or pharmacist.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Remeron Interactions

Tell your healthcare provider about all the medicines that you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. 

Especially tell your doctor if you take:

This is not a complete list of Remeron drug interactions.

Your healthcare provider or pharmacist can tell you if it is safe to take Remeron with your other medicines. Do not start or stop any medicine while taking Remeron without talking to your healthcare provider first.

Remeron Precautions

Remeron and other antidepressant medicines may cause serious side effects, including:

1.  Suicidal thoughts or actions:
  • Antidepressant medicines may increase suicidal thoughts or actions in some children, teenagers, or young adults within the first few months of treatment or when the dose is changed.
  • Depression or other serious mental illnesses are the most important causes of suicidal thoughts or actions.
  • Watch for these changes and call your healthcare provider right away if you notice:
    • New or sudden changes in mood, behavior, actions, thoughts, or feelings, especially if severe.
    • Pay particular attention to such changes when Remeron is started or when the dose is changed.

    Keep all follow-up visits with your healthcare provider and call between visits if you are worried about symptoms.
    Call your healthcare provider right away if you have any of the following symptoms, or call 911 if an emergency, especially if they are new, worse, or worry you:
    • attempts to commit suicide
    • acting on dangerous impulses
    • acting aggressive or violent
    • thoughts about suicide or dying
    • new or worse depression
    • new or worse anxiety or panic attacks
    • feeling agitated, restless, angry or irritable
    • trouble sleeping
    • an increase in activity or talking more than what is normal for you
    • other unusual changes in behavior or mood

Call your healthcare provider right away if you have any of the following symptoms, or call 911 if an emergency. Remeron may be associated with these serious side effects:

  • trouble breathing, swelling of the face, tongue, eyes or mouth
2.  Manic episodes:
  • greatly increased energy
  • severe trouble sleeping
  • racing thoughts
  • reckless behavior
  • unusually grand ideas
  • excessive happiness or irritability
  • talking more or faster than usual
3.  Decreased White Blood Cells called neutrophils, which are needed to fight infections. Tell your doctor if you have any indication of infection such as fever, chills, sore throat, or mouth or nose sores, especially symptoms which are flu-like.
 
4.  Serotonin Syndrome or Neuroleptic Malignant Syndrome-like reactions. This condition can be life-threatening and may include:
  • agitation, hallucinations, coma or other changes in mental status
  • coordination problems or muscle twitching (overactive reflexes)
  • racing heartbeat, high or low blood pressure
  • sweating or fever
  • nausea, vomiting, or diarrhea
  • muscle rigidity
5.  Seizures
 
6.  Low salt (sodium) levels in the blood. Elderly people may be at greater risk for this. Symptoms may include:
  • headache
  • weakness or feeling unsteady
  • confusion, problems concentrating or thinking or memory problems
7.  Sleepiness. It is best to take Remeron close to bedtime.
 
8.  Severe skin reactions: Call your doctor right away if you have any or all of the following symptoms:
  • severe rash with skin swelling (including on the palms of the hands and soles of the feet)
  • painful reddening of the skin and/or blisters/ulcers on the body or in the mouth
9.  Severe allergic reactions:
  • rash, itchy welts (hives) or blisters, alone or with fever or joint pain
10. Increases in appetite or weight. Children and adolescents should have height and weight monitored during treatment.
 
11. Increased cholesterol and triglyceride levels in your blood

Do not stop Remeron without first talking to your healthcare provider. Stopping Remeron too quickly may cause potentially serious symptoms including:

  • dizziness
  • abnormal dreams
  • agitation
  • anxiety
  • fatigue
  • confusion
  • headache
  • shaking
  • tingling sensation
  • nausea, vomiting
  • sweating

Do not take Remeron if you:

  • are allergic to Remeron or any of the ingredients in it.
  • take a Monoamine Oxidase Inhibitor (MAOI). Ask your healthcare provider or pharmacist if you are not sure if you take an MAOI, including the antibiotic linezolid. It is recommended that Remeron not be used in combination with an MAOI within 14 days of initiating or discontinuing therapy with an MAOI. People who take Remeron close in time to an MAOI may have serious or even life-threatening side effects. Get medical help right away if you have any of these symptoms:
  • high fever
  • uncontrolled muscle spasms
  • stiff muscles
  • rapid changes in heart rate or blood pressure
  • confusion
  • loss of consciousness (pass out)

Remeron Food Interactions

Medications can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of Remeron, there are no specific foods that you must exclude from your diet when receiving this medication. Do not drink alcohol while taking this medication.

Inform MD

Before starting Remeron, tell your healthcare provider if you:

  • have or had liver problems
  • have or had kidney problems
  • have or had heart problems
  • have or had seizures or convulsions
  • have or had bipolar disorder or mania
  • have or had a tendency to get dizzy or faint
  • are pregnant or plan to become pregnant. It is not known if Remeron will harm your unborn baby. Talk to your healthcare provider about the benefits and risks of treating depression during pregnancy.
  • are breastfeeding or plan to breastfeed. Some Remeron may pass into your breast milk. Talk to your healthcare provider about the best way to feed your baby while taking Remeron.

Tell your healthcare provider about all the medicines that you take, including prescription and non-prescription medicines, vitamins, and herbal supplements.

Remeron and Pregnancy

Tell your healthcare provider if you are pregnant or plan to become pregnant.

The FDA categorizes medications based on safety for use during pregnancy. Five categories - A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy.

Remeron falls into category C. In animal studies, pregnant animals were given this medication and had some babies born with problems. No well-controlled studies have been done in humans, though. Therefore, this medication may be used if the potential benefits to the mother outweigh the potential risks to the unborn child.

Remeron and Lactation

Tell your healthcare provider if you are breastfeeding or plan to breastfeed. Some Remeron may pass into your breast milk. Talk to your healthcare provider about the best way to feed your baby while taking Remeron.

Remeron Usage

  • Take Remeron at the same time each day, preferably in the evening at bedtime.
  • Swallow Remeron as directed.
  • Do not stop taking or change the dose of Remeron without first talking to your doctor, even if you feel better.
  • Remeron may be taken with or without food.
  • If you miss a dose of Remeron, take the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and take your next dose at the regular time. Do not take two doses of Remeron at the same time.
  • If you take too much Remeron, call your healthcare provider or poison control center right away, or get emergency treatment.
  • Remeron can cause sleepiness or may affect your ability to make decisions, think clearly, or react quickly. You should not drive, operate heavy machinery, or do other dangerous activities until you know how Remeron affects you.
  • Avoid drinking alcohol or taking diazepam (a medicine used for anxiety, insomnia and seizures, for example) or similar medicines while taking Remeron. If you are uncertain about whether certain medication can be taken with Remeron, please discuss with your doctor.

Remeron Dosage

Take this medication exactly as prescribed by your doctor. Follow the directions on your prescription label carefully.

The dose your doctor recommends may be based on the following:

  • how you respond to this medication
  • your age
  • your renal function
  • your hepatic function

The recommended starting dose for Remeron is 15 mg/day, administered in a single dose, in the evening prior to sleep.

The recommended dose range of Remeron for the treatment of depression is 15 to 45 mg/day.

Remeron Overdose

If you take too much Remeron, call your healthcare provider or poison control center right away, or get emergency treatment.

Other Requirements

  • Store Remeron at room temperature 25°C (77°F). Storage at 15°C-30°C (59°F-86°F) is permitted occasionally.
  • Keep Remeron away from light and moisture.

Keep this and all medicines out of the reach of children.

Remeron FDA Warning

Suicidality and Antidepressant Drugs

Antidepressants increased the risk compared to placebo of suicidal thinking and behavior (suicidality) in children, adolescents, and young adults in short-term studies of major depressive disorder (MDD) and other psychiatric disorders. Anyone considering the use of Remeron or any other antidepressant in a child, adolescent, or young adult must balance this risk with the clinical need. Short-term studies did not show an increase in the risk of suicidality with antidepressants compared to placebo in adults beyond age 24; there was a reduction in risk with antidepressants compared to placebo in adults aged 65 and older. Depression and certain other psychiatric disorders are themselves associated with increases in the risk of suicide. Patients of all ages who are started on antidepressant therapy should be monitored appropriately and observed closely for clinical worsening, suicidality, or unusual changes in behavior. Families and caregivers should be advised of the need for close observation and communication with the prescriber. Remeron is not approved for use in pediatric patients.