Medication

Paxil

Generic name:

Pharmacist-reviewed drug information from the RxWiki encyclopedia.

Overview

Paxil (paroxetine) is an oral medication used primarily to treat major depressive disorder and generalized anxiety disorder. It has also been used to treat obsessive-compulsive disorder, panic disorder, social anxiety disorder, pre-menstrual dysphoric disorder, and post-traumatic stress disorder. It is part of a class of medications called selective serotonin reuptake inhibitors (SSRIs). It works by increasing the levels of serotonin in the brain, a neurotransmitter chemical that plays an important role in maintaining mood signals in the brain.

It is believed that a possible cause of depression is a low amount of the neurotransmitter serotonin. In the brain, the space between where two neurons meet to communicate is called a synapse, and the synapse is where serotonin is used to communicate between neurons. In depression, people may not have enough serotonin in their brain. Normally after a chemical message is sent between neurons, the serotonin is reabsorbed by the sending neuron (presynaptic neuron). A selective serotonin reuptake inhibitor will bind to the presynaptic neuron and prevent it from absorbing the serotonin, and leaving the neurotransmitter active in the synapse, and improving mood.

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