Nimotop

Nimotop is a prescription medicine used to treat patients experiencing symptoms of ruptured blood vessels in the brain (subarachnoid hemorrhage, or SAH). Nimotop belongs to a group of drugs called calcium channel blockers, which relax blood vessels, making it easier for blood to flow into the injured brain tissue.

Nimotop is a prescription medication used to treat patients experiencing symptoms resulting from ruptured blood vessels in the brain (subarachnoid hemorrhage). A subarachnoid hemorrhage is serious, life threatening bleeding that occurs in the subarachnoid space – the area between the brain and the thin tissues that cover the brain.

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

The recommended oral dosage of Nimotop is 60 mg every 4 hours for 21 consecutive days. 

For people with cirrhosis (scarring of the liver), the dose of Nimotop is reduced to 30 mg every 4 hours.

Serious side effects have been reported with Nimotop including:

• hypotension. Hypotension, or low blood pressure, may cause you to feel faint or dizzy. Inadequate fluid intake, excessive sweating, diarrhea, or vomiting can lead to an excessive fall in blood pressure, too. Lie down if you feel faint or dizzy. Call your doctor right away.
• cirrhosis (scarring of the liver). People already diagnosed with cirrhosis are at an increased risk of serious side effects. Your doctor may want to monitor blood pressure and pulse rate closely and administer a lower dosage of Nimotop.

Nimotop can cause dizziness. Do not drive or operate heavy machinery until you know how Nimotop affects you.

Serious side effects have been reported with Nimotop. See "Drug Precautions" section.

The most common side effects reported in clinical trials include:

• decreased blood pressure
• dizziness
• headache
• nausea
• slower than normal heartbeat
• rash

This is not a complete list of Nimotop side effects. Ask your doctor or pharmacist for more information. 

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your doctor if you take:

• macrolide antibiotics such as clarithromycin (Biaxin) and telithromycin (Ketek)
• HIV protease inhibitors such as indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir), and saquinavir (Invirase)
• some HCV protease inhibitors such as boceprevir (Victrelis) and telaprevir (Incivek)
• some azole antimycotics such as ketoconazole (Nizoral), itraconazole (Onmel, Sporanox), posaconazole (Noxafil), and voriconazole (Vfend)
• conivaptan (Vaprisol)
• delavirdine (Rescriptor)
• nefazodone (Serzone)
• carbamazepine (Tegretol, Equetro, Carbatrol)
• phenobarbital
• phenytoin (Dilantin)
• rifampin (Rifadin)
• St John’s wort
• blood pressure lowering medications, including diuretics, beta-blockers, ACE inhibitors, angiotensin receptor blockers (ARBs), other calcium channel blockers, α-adrenergic blockers, PDE5 inhibitors, and α-methyldopa. Ask your pharmacist if you are taking these type of medications.

This is not a complete list of Nimotop drug interactions. Ask your doctor or pharmacist for more information.

Tell your doctor if you are pregnant or plan to become pregnant.

The FDA categorizes medications based on safety for use during pregnancy. Five categories - A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy.

Nimotop falls into category  C. There are no well-controlled studies in pregnant women. Nimotop should be used during pregnancy only if the possible benefit outweighs the possible risk to the unborn baby.

Tell your doctor if you are breastfeeding or plan to breastfeed.

It is not known if Nimotop crosses into human milk. Because many medications can cross into human milk and because of the possibility for serious adverse reactions in nursing infants with use of this medication, a choice should be made whether to stop nursing or stop the use of this medication. Your doctor and you will decide if the benefits outweigh the risk of using Nimotop.

Take medication 1 before a meal or 2 hours after a meal.

Nimodipine capsules should be swallowed whole with a little liquid.

Nimodipine can cause hypotension. Hypotension, or low blood pressure, may cause you to feel faint or dizzy. Lie down if you feel faint or dizzy. Call your doctor right away.

Nimodipine can cause dizziness. Do not drive or operate heavy machinery until you know how nimodipine affects you.

Grapefruit and grapefruit juice may interact with nimodipine and lead to potentially dangerous effects. Discuss the use of grapefruit products with your doctor.