Namenda XR
Generic name: memantine
Pharmacist-reviewed drug information from the RxWiki encyclopedia.
Overview
Namenda XR is a prescription medication used to treat Alzheimer's disease. Namenda XR is in a class of medications called NMDA receptor antagonists. It works by decreasing abnormal activity in the brain.
Namenda XR is available as an extended release capsule and is taken once daily.
Common side effects of Namenda XR include tiredness, dizziness, headache, and confusion. Do not drive or operate heavy machinery until you know how Namenda XR affects you.
What is it used for?
Namenda XR is a prescription medication used to treat the symptoms of Alzheimer's disease.
This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.
How to take it
- The recommended starting dose of Namenda XR is 7 mg once daily. The recommended target dose is 28 mg once daily. The dose should be increased in 7 mg increments to 28 mg once daily.
Warnings
You should not take Namenda XR if you are allergic to any of its ingredients. Tell your doctor if you are allergic to Namenda XR or any other medicines.
Namenda XR can make you drowsy. Do not drive a car or operate machinery until you know how this medicine affects you.
Poor liver or kidney function can lead to an increase in the level of Namenda XR in the body. This may increase your risk of side effects. Tell your doctor if you have liver or kidney disease.
Side effects
Namenda XR may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- extreme tiredness
- dizziness
- confusion
- headache
- sleepiness
- constipation
- vomiting
- pain anywhere in your body, especially your back
- coughing
Some side effects can be serious. The following symptoms are uncommon, but if you experience any of them, call your doctor immediately:
- shortness of breath
- hallucination (seeing things or hearing voices that do not exist)
Namenda XR may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
Drug interactions
Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your doctor if you take:
- acetazolamide (Diamox);
- amantadine (Symmetrel);
- brinzolamide (Azopt);
- cimetidine (Tagamet);
- dextromethorphan (Robitussin, others);
- dichlorphenamide (Daranide);
- dorzolamide (Trusopt);
- methazolamide (GlaucTabs, Nepatazane);
- nicotine (Nicoderm, Nicorette, others);
- potassium citrate and citric acid (Cytra-K, Polycitra-K);
- ranitidine (Zantac);
- sodium bicarbonate (Soda Mint, baking soda);
- sodium citrate and citric acid (Bicitra, Oracit);
- and quinidine (Quinaglute, Quinidex)
This is not a complete list of Namenda XR drug interactions. Ask your doctor or pharmacist for more information.
Pregnancy
Tell your doctor if you are pregnant or plan to become pregnant.
The FDA categorizes medications based on safety for use during pregnancy. Five categories - A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy.
Namenda XR falls into category B. There are no well-done studies that have been done in humans with Namenda XR. But in animal studies, pregnant animals were given this medication, and the babies did not show any medical issues related to this medication.
Breastfeeding
It is not known if Namenda XR crosses into human milk. Because many medications can cross into human milk and because of the possibility for serious adverse reactions in nursing infants with use of this medication, a choice should be made whether to stop nursing or stop the use of this medication. Your doctor and you will decide if the benefits outweigh the risk of using Namenda XR.
Quick facts
Your doctor will probably start you on a low dose of memantine and gradually increase your dose, not more than once every week.
Tell your doctor if you use tobacco products. Cigarette smoking may decrease the effectiveness of this medication.
All information on this site is provided “as-is” for informational purposes only and is not a substitute for medical advice or treatment. You should consult with a medical professional if you have any questions about your health.