Glucotrol

Glucotrol is a prescription medication used to treat type 2 diabetes. Glucotrol belongs to a group of drugs called sulfonylureas, which help lower blood sugar levels by causing the pancreas to secrete insulin.

This medication comes in tablet form and is taken one or more times a day before meals.

Common side effects of Glucotrol include nausea, diarrhea, and gas. Glucotrol can cause dizziness. Do not drive or operate machinery until you know how Glucotrol affects you.

 

Glucotrol is a prescription medication used to treat type 2 diabetes. Glucotrol lowers blood sugar levels along with exercise and an appropriate diet.

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

Take Glucotrol exactly as prescribed by your doctor. Follow the directions on your prescription label carefully.

The dosage range for Glucotrol is between 2.5 and 40 mg each day. The maximum once daily dose is 15 mg. Amounts above 15 mg per day should be split into different doses throughout the day. The maximum daily dose is 40 mg.

Serious side effects have been reported with Glucotrol including:

• Glucotrol may increase your chance of death from heart disease.
• Glucotrol can cause low blood sugar levels (hypoglycemia) in patients. Tell your doctor if you have a history of kidney or liver disease or drink alcohol. Symptoms of low blood sugar include:
  • shakiness
  • tremors
  • cold sweat
  • fast heart rate
  • headache
  • moodiness
  • dizziness
  • blurred vision
  • confusion
• After exposure to stress, such as fever, trauma, infection, or surgery, glipizide may cause you to lose control over your blood glucose levels.
• Glucotrol can decrease the number of red blood cells in people with glucose-6-phosphate dehydrogenase (G6PD) deficiency.  Alert your doctor if you have a history of G6PD deficiency or anemia.
• A severe allergic reaction to Glucotrol is possible. Tell your healthcare provider right away if you have some or all of the following symptoms of a hypersensitivity reaction:
  • difficulty breathing or swallowing
  • hoarseness
  • rash or hives
  • swelling
• Glucotrol can cause dizziness.  Do not drive or operate machinery until you know how Glucotrol affects you. Alcohol may increase the severity of side effects.

Do not take Glucotrol if you:

• are allergic to glipizide (Glucotrol)
• have type 1 diabetes

Serious side effects have been reported with Glucotrol. See “Drug Precautions” section.

Common side effects of Glucotrol include:

• nausea
• diarrhea
• gas
• weakness
• nervousness
• headache
• shakiness
• dizziness

This is not a complete list of Glucotrol side effects. Ask your doctor or pharmacist for more information.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your doctor if you take:

• non-steroidal anti-inflammatory drugs (NSAIDs), such as aspirin (Ecotrin), ibuprofen (Advil), naproxen (Aleve, Naprosyn), and others
• azoles, such as miconazole (Lotrimin and Monistat) and fluconazole (Diflucan)
• salicylic acid containing products, such as Pepto-Bismol
• chloramphenicol (Chloromycetin)
• probenecid (Probalan)
• anticoagulants, or "blood thinners", such as warfarin (Coumadin, Jantoven)
• monoamine oxidase (MAO) inhibitors, such as selegiline (Emsam), phenelzine (Nardil), and others
• beta-adrenergic blocking agents (beta blockers), such as atenolol (Tenormin), propranolol (Inderal) metoprolol (Lopressor), and others
• diuretics such as hydrochlorothiazide (Microzide, HCTZ), furosemide (Lasix), and others
• corticosteroids such as hydrocortisone (Cortef), prednisone (Deltasone), methylprednisolone (Medrol), triamcinolone (Kenalog, Aristospan), and others
• thyroid products such as levothyroxine (Levothroid, Levoxyl, Synthroid, Tirosint, Unithroid), thyroid (Armour Thyroid), and others
• estrogens
• oral contraceptives (birth control pills)
• phenytoin (Dilantin)
• nicotinic acid, or niacin (Niaspan, Niacor, Nicolar)
• albuterol (Proventil) 
• calcium channel blockers, such as amlodipine (Norvasc), diltiazem (Cardizem, Dilacor, Tiazac), nifedipine (Adalat, Procardia), and Verapamil (Calan, Verelan), and others
• isoniazid
• phenothiazine medications such as promethazine (Phenergan), thioridazine (Mellaril), and others

This is not a complete list of Glucotrol drug interactions. Ask your doctor or pharmacist for more information.

Tell your doctor if you are pregnant or plan to become pregnant.

The FDA categorizes medications based on safety for use during pregnancy. Five categories - A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy.

Glucotrol falls into category C. Studies in animals have shown a harmful and undesired effect on the unborn baby, yet there are no adequate and well-controlled studies in pregnant women.

• This medication may be given to a pregnant woman if her healthcare provider believes that its benefits to the pregnant woman outweigh any possible risks to her unborn baby.
• Many experts encourage pregnant mothers to take insulin to treat their high blood sugar levels. Glucotrol should not be taken in the last month of pregnancy.

Tell your doctor if you are breastfeeding or plan to breastfeed.

You should not take Glucotrol if you are breastfeeding. It may be excreted in your breast milk and may harm your nursing child.

Glipizide can cause low blood sugar levels (hypoglycemia) in patients. Make sure you know the signs and symptoms of low blood sugar.

Alcohol can intensify the side effects of glipizide.

Glipizide should be taken with a healthy diet to maximize its blood glucose lowering effects.

After exposure to stress, such as fever, trauma, infection, or surgery, glipizide may cause you to lose control over your blood glucose levels.