Claforan

Claforan is a prescription medication used to treat bacterial infections, including lung, skin, joint, bone, urinary tract, and gynecological infections. Claforan belongs to a group of drugs called cephalosporin antibiotics, which work to stop the growth of bacteria in the body.

This medication is available in an injectable form to be given directly into a vein (IV) or muscle (IM) by a healthcare professional.

Common side effects of Claforan include irritation at the site of injection, rash, itching, diarrhea, and nausea.

Claforan is a prescription medication used to treat bacterial infections, including lung, skin, joint, bone, urinary tract, and gynecological infections.

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

Take Claforan exactly as prescribed by your doctor. Follow the directions on your prescription label carefully.

The Claforan dose your doctor recommends will be based on (use any or all that apply):

• the condition being treated
• other medical conditions you have
• other medications you are taking
• how you respond to this medication
• your kidney function
• your weight
• your age

The recommended dose range for Claforan in adults is 0.5 grams once a day to 12 grams divided into multiple doses per day.

The recommended dose range for Claforan in children includes the following.

• 0 to 1 week of age – 50 mg/kg per dose every 12 hours IV
• 1 to 4 weeks of age – 50 mg/kg per dose every 8 hours IV
• If 1 month to 12 years old:
  • Less than 50 kg – 50 to 180 mg/kg IM or IV divided into four to six equal doses
  • Greater than or equal to 50 kg – use the usual adult dose (max dose of 12 grams)

Serious side effects have been reported with Claforan including the following:

• hypersensitivity (severe allergic reaction). Signs of a hypersensitivity reaction, which include the following:
  • chest pain
  • swelling of the face, eyes, lips, tongue, arms, or legs
  • difficulty breathing or swallowing
  • fainting
  • rash
• diarrhea. Diarrhea is a common problem caused by antibiotics, and it usually ends when the antibacterial is discontinued. Sometimes after starting treatment with antibiotics, patients can develop watery and bloody stools (with or without stomach cramps and fever) even as late as 2 or more months after having taken their last dose of the antibacterial. If diarrhea is severe or lasts more than 2 or 3 days, contact your doctor, as this may be a sign of an infection of the bowels.
• superinfection. Claforan should not be used for extended periods. Prolonged use can lead to the growth of dangerous organisms that are resistant or unresponsive to this medication. Take Maxipime for the duration prescribed by your doctor.

Do not take Claforan if you:

• are allergic to Claforan or to any of its ingredients
• are allergic to similar antibiotics (penicillins, cephalosporins)

Common side effects of Claforan include:

• irritation at the site of injection
• diarrhea
• rash
• itching
• diarrhea
• nausea
• vomiting
• fever

This is not a complete list of Claforan side effects. Ask your doctor or pharmacist for more information.

Serious side effects have been reported with Claforan. See the “Drug Precautions” section.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your doctor if you take:

• aminoglycosides such as amikacin (Amikin), gentamicin (Garamycin), and tobramycin (Nebcin)
• probenecid (Probalan, Benemid)
• methotrexate (Trexall, Rheumatrex)
• birth control pills

This is not a complete list of Claforan drug interactions. Ask your doctor or pharmacist for more information.

Tell your doctor if you are pregnant or plan to become pregnant.

The FDA categorizes medications based on safety for use during pregnancy. Five categories - A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy.

Claforan falls into category B. There are no well-done studies that have been done in humans with Claforan. But in animal studies, pregnant animals were given this medication, and the babies did not show any medical issues related to this medication.

Tell your doctor if you are breastfeeding or plan to breastfeed.

Claforan has been detected in human breast milk. Because of the possibility for adverse reactions in nursing infants from Claforan, a choice should be made whether to stop nursing or to stop use of Claforan. The importance of the drug to the mother should be considered.

Before taking cefotaxime, tell your doctor if you are allergic to similar antibiotics (penicillins, cephalosporins).

Diarrhea is a common problem caused by antibiotics. Sometimes patients can develop watery and bloody stools even as late as 2 or more months after having taken their last dose of the antibacterial. If diarrhea is severe or lasts more than 2 or 3 days, contact your doctor.

Cefotaxime can interact with other medications. Tell your doctor if you take birth control pills.