Condition

Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis (ALS) is a progressive disease of the nervous system.

Neurology

Overview

Amyotrophic Lateral Sclerosis (ALS) is a progressive disease of the nervous system. Motor neurons that control movement throughout the body are rapidly and progressively destroyed.

The onset of ALS usually occurs between age 40 and 70, and more men are diagnosed with ALS than women. The cause of ALS is not known. It can run in families, but most cases of ALS are random and can affect anyone.

ALS is always fatal, but medications and treatments can improve symptoms and prolong survival.

ALS is also known as “Lou Gehrig’s Disease” in memory of one of its most famous victims.

Symptoms

  • Trouble walking or running
  • Tripping
  • Dropping things
  • Trouble writing
  • Speech problems
  • Uncontrollable episodes of laughing or crying

Causes & risk factors

The cause of ALS is unknown. Genetics and environmental factors may contribute to the disease, and research is underway to confirm potential causes and contributing factors.

A very small portion of cases are a familial form of the disease that is inherited, but most cases occur at random and there are no identified risk factors for the disease.

When to get help

See a doctor if you have progressive muscle weakness, frequent tripping, slurred speech, or trouble swallowing. Early diagnosis helps you access treatments and support that can improve quality of life.

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All information on this site is provided “as-is” for informational purposes only and is not a substitute for medical advice or treatment. You should consult with a medical professional if you have any questions about your health.