Stendra (generic: avanafil) is a prescription medication used to treat erectile dysfunction in adult men. Stendra belongs to a group of drugs called phosphodiesterase (PDE5) inhibitors, which increase blood flow to the penis during sexual stimulation.
This medication comes in the form of a fast-acting tablet to be taken 30 minutes before sexual activity, with or without food. Do not take more than one tablet a day.
Common side effects of Stendra include headache, flushing, and stuffy nose.
Stendra is a prescription medicine used to treat adult men with erectile dysfunction (ED).
This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.
The most common side effects of Stendra are:
- stuffy or runny nose
- sore throat
- back pain
Stendra may uncommonly cause:
- an erection that will not go away (priapism). If you have an erection that lasts more than 4 hours, get medical help right away.
- sudden vision loss in 1 or both eyes. Sudden vision loss in 1 or both eyes can be a sign of a serious eye problem called non-arteritic anterior ischemic optic neuropathy (NAION). Stop taking Stendra and call your healthcare provider right away if you have sudden vision loss in 1 or both eyes.
- sudden hearing decrease or hearing loss. Some people may also have ringing in their ears (tinnitus) or dizziness.
Tell your healthcare provider about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Stendra may affect the way other medicines work, and other medicines may affect the way Stendra works causing side effects. Especially tell your healthcare provider if you take any of the following:
- medicines called nitrates
- medicines called HIV protease inhibitors, such as ritonavir (Norvir), indinavir (Crixivan), saquinavir (Fortavase or Invirase) or atazanir (Reyataz)
- some types of oral antifungal medicines, such as ketoconazole (Nizoral), and itraconozale (Sporonox)
- some types of antibiotics, such as clarithromycin (Biaxin), telithromycin (Ketek), or erythromycin
- medicines called alpha blockers. These include Hytrin (terazosin), Flomax (tamsulosin HCl), Cardura (doxazosin), Minipress (prazosin HCl), Uroxatral (alfuzosin HCl), Jalyn (dutasteride and tamsulosin HCl), or Rapaflo (silodosin). Alpha-blockers are sometimes prescribed for prostate problems or high blood pressure. In some patients, the use of Stendra with alpha-blockers can lead to a drop in blood pressure or to fainting.
- other medicines that treat high blood pressure
- other medicines or treatments for ED
Stendra can cause your blood pressure to drop suddenly to an unsafe level if it is taken with certain other medicines. Do not take Stendra if you take any medicines called “nitrates.” Nitrates are used to treat chest pain (angina). A sudden drop in blood pressure can cause you to feel dizzy, faint, or have a heart attack or stroke.
- take medicines called “nitrates”
- use street drugs called “poppers” such as amyl nitrate and butyl nitrate
- are allergic to avanafil or any of the ingredients in Stendra.
Medicines can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. Do not drink too much alcohol when taking Stendra (for example, 3 glasses of wine, or 3 shots of whiskey). Drinking too much alcohol when taking Stendra can increase your chances of getting a headache or getting dizzy, increasing your heart rate, or lowering your blood pressure.
Before you take Stendra, tell your healthcare provider if you:
- have or have had heart problems such as a heart attack, irregular heartbeat, angina, or heart failure
- have had heart surgery within the last 6 months
- have had a stroke
- have low blood pressure, or high blood pressure that is not controlled
- have a deformed penis shape
- have had an erection that lasted for more than 4 hours
- have problems with your blood cells such as sickle cell anemia, multiple myeloma, or leukemia
- have retinitis pigmentosa, a rare genetic (runs in families) eye disease
- have ever had severe vision loss, including an eye problem called non-arteritic anterior ischemic optic neuropathy (NAION)
- have bleeding problems
- have or have had stomach ulcers
- have liver problems
- have kidney problems or are having kidney dialysis
- have any other medical conditions
Stendra is not for use in women. There are no studies of Stendra in pregnant women. It is not known if Stendra will harm your unborn baby.
Stendra is not for use in women. There are no studies of Stendra in breastfeeding women.
- Take Stendra exactly as your healthcare provider tells you to take it. Your healthcare provider will tell you how much Stendra to take and when to take it.
- Take Stendra about 30 minutes before sexual activity.
- Do not take Stendra more than 1 time a day.
- Your healthcare provider may change your dose if needed.
- You should take the lowest dose of Stendra that works for you. You and your healthcare provider should decide about the lowest dose of Stendra that works for you.
- Stendra may be taken with or without food.
- Do not drink too much alcohol when taking Stendra (for example, 3 glasses of wine, or 3 shots of whiskey). Drinking too much alcohol when taking Stendra can increase your chances of getting a headache or getting dizzy, increasing your heart rate, or lowering your blood pressure.
Take Stendra exactly as prescribed by your doctor. Follow the directions on your prescription label carefully.
The recommended starting dose is 100 mg taken approximately 30 minutes before sexual activity, no more than once a day. The dose may be increased to 200 mg or decreased to 50 mg depending on the effectiveness of Stendra and how well it is tolerated.
If you take too much Stendra, call your local Poison Control Center or seek emergency medical attention right away.
Stendra tablets are available in the following strengths: 50 mg, 100 mg, and 200 mg.
- Store Stendra at 68°F to 77°F (20°C to 25°C).
- Keep Stendra out of the light.
- Keep Stendra and all medicines out of the reach of children