Protopam Chloride

Protopam is used to treat poisoning and drug overdose. It may cause pain where the injection was given.

Protopam Chloride Overview


Protopam is a prescription medication used to treat drug overdose and poisoning. Protopam belongs to a group of drugs called nerve gas antidotes. These work by reactivating a substance in the body that nerve gas deactivates.

Protopam is available in an injectable form to be given directly into a vein (IV), or muscle (IM) by a healthcare professional.

Common side effects of Protopam include headache, nausea, and increased heart rate. 

Protopam can also cause dizziness. Do not drive or operate heavy machinery until you know how Protopam affects you.

Patient Ratings for Protopam Chloride

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  • Other
  • Drug Overdose
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Uses of Protopam Chloride

Protopam is a prescription medication used to treat muscle weakness and trouble breathing due to poisoning by nerve agents or pesticides. It is also used to treat overdose of certain medications used to treat myasthenia gravis. Myasthenia gravis is a condition that causes weakness.

This medication may be prescribed for other uses.  Ask your doctor or pharmacist for more information.



For more information on this medication choose from the list of selections below.

Protopam Chloride Drug Class

Protopam Chloride is part of the drug class:

Side Effects of Protopam Chloride

Serious side effects have been reported with Protopam. See the "Drug Precautions" section.

Common side effects of Protopam include the following:

  • headache
  • blurred vision
  • nausea
  • increased heart rate
  • increased blood pressure
  • muscle weakness
  • injection site pain
  • dizziness

This is not a complete list of Protopam side effects. Ask your doctor or pharmacist for more information.

Tell your doctor if you have any side effect that bothers you or that does not go away.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.