Pralidoxime is used to treat poisoning and drug overdose. It may cause pain where the injection was given.

Pralidoxime Overview


Pralidoxime is a prescription medication used to treat drug overdose and poisoning.  Pralidoxime belongs to a group of drugs called nerve gas antidotes.  These work by reactivating a substance in the body that nerve gas deactivates.

Pralidoxime is available in an injectable form to be given directly into a vein (IV), or muscle (IM) by a healthcare professional.

Common side effects of pralidoxime include headache, nausea, and increased heart rate. 

Pralidoxime can also cause dizziness.  Do not drive or operate heavy machinery until you know how pralidoxime affects you.

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Pralidoxime Cautionary Labels


Uses of Pralidoxime

Pralidoxime is a prescription medication used to treat muscle weakness and trouble breathing due to poisoning by nerve agents or pesticides.  It is also used to treat overdose of certain medications used to treat myasthenia gravis. Myasthenia gravis is a condition that causes weakness.

This medication may be prescribed for other uses.  Ask your doctor or pharmacist for more information.

Pralidoxime Brand Names

Pralidoxime may be found in some form under the following brand names:

Pralidoxime Drug Class

Pralidoxime is part of the drug class:

Side Effects of Pralidoxime

Serious side effects have been reported with pralidoxime.  See the "Drug Precautions" section.

Common side effects of pralidoxime include the following:

  • headache
  • blurred vision
  • nausea
  • increased heart rate
  • increased blood pressure
  • muscle weakness
  • injection site pain
  • dizziness

This is not a complete list of pralidoxime side effects.  Ask your doctor or pharmacist for more information.

Tell your doctor if you have any side effect that bothers you or that does not go away.

Call your doctor for medical advice about side effects.  You may report side effects to the FDA at 1-800-FDA-1088.