Mirapex ER

Mirapex ER treats signs and symptoms of Parkinson's disease. If Mirapex ER causes nausea, try to take it with food.

Mirapex ER Overview

Reviewed: August 21, 2012
Updated: 

Mirapex ER is a prescription medication used to treat Parkinson's Disease. Mirapex ER belongs to a group of drugs called dopamine agonists which work by binding to dopamine receptors in the brain, helping to control movement.

Mirapex ER comes as an extended release tablet and is taken once a day, with or without food. Swallow extended release tablet whole. Do not chew, crush, or divide extended release tablets.

Common side effects include nausea, dizziness, and drowsiness. Do not drive or operate heavy machinery until you know how this medication affects you.

Patient Ratings for

How was your experience with ?

First, a little about yourself

Tell us about yourself in a few words?

What tips would you provide a friend before taking ?

What are you taking for?

Choose one
  • Other
  • Depressive Disorder
  • Parkinson Disease

How long have you been taking it?

Choose one
  • Less than a week
  • A couple weeks
  • A month or so
  • A few months
  • A year or so
  • Two years or more

How well did work for you?

Did you experience many side effects while taking this drug?

How likely would you be to recommend to a friend?

Mirapex ER Cautionary Labels

precautionsprecautionsprecautionsprecautionsprecautions

Uses of Mirapex ER

Mirapex ER tablets is a prescription medicine used to treat signs and symptoms of Parkinson's disease.

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

Manufacturer

Mirapex ER Drug Class

Mirapex ER is part of the drug class:

Side Effects of Mirapex ER

Mirapex ER may cause serious side effects. See "Drug Precautions" section.

The most common side effects in people taking Mirapex ER for Parkinson’s disease are nausea, dizziness, sleepiness, constipation, hallucinations, insomnia, muscle weakness, confusion, and abnormal movements.

Mirapex ER Interactions

Tell your doctor about all the medicines you take including prescription and nonprescription medications, vitamins, nutritional supplements and herbal products. Be sure to mention any of the following:

  • amantadine (Symadine, Symmetrel)
  • antidepressants
  • antihistamines
  • cimetidine (Tagamet)
  • diltiazem (Cardiazem, Dilacor XR)
  • levodopa (Larodopa, Dopar, in Sinemet)
  • medications for allergies, anxiety, mental illness, nausea, and seizure
  • metoclopramide (Reglan)
  • quinidine
  • quinine
  • ranitidine (Zantac, Zantac 75)
  • sedatives
  • sleeping pills
  • tranquilizers
  • triamterene (Dyrenium, in Dyazide, in Maxzide)
  • and verapamil (Isoptin, Calan, Verelan, and others)

This is not a complete list of Mirapex ER drug interactions. Ask your doctor or pharmacist for more information.

Mirapex ER Precautions

Mirapex ER may cause serious side effects, including:

  • falling asleep during normal daily activities. Mirapex ER may cause you to fall asleep while you are doing daily activities such as driving, talking with other people, or eating.
    • Some people taking the medicine in Mirapex ER have had car accidents because they fell asleep while driving.
    • Some patients did not feel sleepy before they fell asleep while driving. You could fall asleep without any warning.
      Tell your doctor right away if you fall asleep while you are doing activities such as talking, eating, driving, or if you feel sleepier than normal for you.
  • low blood pressure when you sit or stand up quickly. You may have:
    • dizziness
    • nausea
    • fainting
    • sweating
      Sit and stand up slowly after you have been sitting or lying down.
  • unusual urges. Some people who take certain medicines to treat Parkinson’s disease, including Mirapex ER, have reported problems, such as gambling, compulsive eating, compulsive buying, and increased sex drive.
    If you or your family members notice that you are developing unusual urges or behaviors, talk to your doctor.
  • seeing visions, hearing sounds or feeling sensations that are not real (hallucinations). Your chance of having hallucinations is higher if you are elderly (age 65 or older).
    If you have hallucinations, talk with your doctor right away.
  • uncontrolled sudden movements (dyskinesia). If you have new dyskinesia or your existing dyskinesia gets worse tell your doctor.
  • skin cancer (melanoma). Some people with Parkinson’s disease may have a higher chance of having melanoma than people who do not have Parkinson’s disease. It is not known if the chance of having melanoma is higher because of the medicines to treat Parkinson’s disease, like Mirapex ER, or from the Parkinson’s disease. People who take Mirapex ER should have regular skin examinations to check for melanoma.

Do not drink alcohol while taking Mirapex ER. It can increase your chance of having serious side effects. 

Do not drive a car, operate a machine, or do other dangerous activities until you know how Mirapex ER affects you. Sleepiness caused by Mirapex ER can happen as late as 1 year after you start your treatment.

Mirapex ER Food Interactions

Medicines can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of Mirapex ER there are no specific foods that you must exclude from your diet when receiving this medication.

Inform MD

Tell your doctor about all of your medical conditions, including if you:

  • are allergic to Mirapex ER or any other medicine
  • feel sleepy during the day from a sleep problem other than Restless Legs Syndrome
  • have low blood pressure, or if you feel dizzy or faint, especially when getting up from a lying or sitting position
  • have trouble controlling your muscles (dyskinesia)
  • have kidney problems
  • are pregnant or breastfeeding
  • drink alcohol. Alcohol can increase the chance that Mirapex ER will make you feel sleepy or fall asleep when you should be awake.

Tell your doctor about all of the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements.

Mirapex ER and Pregnancy

Tell your doctor if you are pregnant or plan to become pregnant.

The FDA categorizes medications based on safety for use during pregnancy. Five categories - A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy.

Mirapex ER falls into category C. There are no well-controlled studies in pregnant women. Mirapex ER should be used during pregnancy only if the possible benefit outweighs the possible risk to the unborn baby.

Mirapex ER and Lactation

Tell your doctor if you are breastfeeding or plan to breastfeed. It is not known if Mirapex ER is excreted in human breast milk or if it will harm your nursing baby.

Mirapex ER Usage

  • Take Mirapex ER exactly as your doctor tells you to. Your doctor will tell you how many Mirapex ER tablets to take and when to take them.
  • Your doctor may change your dose until you are taking the right amount of medicine to control your symptoms. Do not take more or less Mirapex ER than your doctor tells you to.
  • Mirapex ER can be taken with or without food. Taking Mirapex ER with food may lower your chances of getting nausea.
  • Swallow extended release tablet whole. Do not chew, crush, or divide extended release tablets.
  • If you miss a dose, do not double your next dose. Skip the dose you missed and take your next regular dose.
  • Be sure to tell your doctor right away if you stop taking Mirapex ER for any reason. Do not start taking Mirapex ER again before speaking with your doctor. If you have Parkinson’s disease and are stopping Mirapex ER, you should stop pramipexole slowly over 7 days.

Mirapex ER Dosage

Take Mirapex ER exactly as prescribed by your doctor. Follow the directions on your prescription label carefully. Mirapex ER comes as an extended release tablet to take by mouth.

Mirapex ER tablets when treating Parkinson's disease, is usually taken once a day.

The recommended starting dose is 0.375 mg given once daily. The maximum recommended dose is 4.5 mg per day.

Mirapex ER Overdose

If you take too much Mirapex ER, call your local Poison Control Center or seek emergency medical attention right away.

Other Requirements

  • StoreMirapex ER tablets at room temperature [77°F (25°C)]. Short-term exposure to higher or lower temperatures [from 59°F (15°C) to 86°F (30°C)] is acceptable. Ask your doctor or pharmacist if you have any questions about storing your tablets.
  • Keep Mirapex ER out of light.
  • Keep Mirapex ER and all medicines out of the reach of children.