Lortab

Lortab treats moderate to moderately severe pain. This drug can lead to abuse and dependence, as well as accidental overdoses.

Lortab Overview

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Lortab is a prescription medication used to treat moderate to moderately severe pain.

It is a single product containing 2 medications: hydrocodone and acetaminophen. Hydrocodone belongs to a group of drugs called narcotic analgesics. These work by changing the way that the brain and nervous system respond to pain. Acetaminophen belongs to a group of drugs called analgesics and antipyretics. These work by changing the way the body feels pain and by cooling the body.

This medication comes in tablet and oral syrup forms and is taken every 4 to 6 hours.

Common side effects of Lortab include lightheadedness, sedation, nausea, and vomiting.

Lortab can also cause drowsiness and dizziness. Do not drive or operate heavy machinery until you know how Lortab affects you.

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Lortab Cautionary Labels

precautionsprecautions

Uses of Lortab

Lortab is a prescription medication used to treat moderate to moderately severe pain.

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

Manufacturer

Side Effects of Lortab

Serious side effects have been reported with Lortab. See the “Lortab Precautions” section.

Common side effects of Lortab include the following:

  • lightheadedness
  • dizziness
  • sedation
  • nausea and vomiting

This is not a complete list of Lortab side effects. Ask your doctor or pharmacist for more information.

Tell your doctor if you have any side effect that bothers you or that does not go away.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Lortab Interactions

Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your doctor if you take:

  • other narcotic analgesics
  • antihistamines such as diphenhydramine (Benadryl)
  • antipsychotics such as paliperidone (Invega), lurasidone (Latuda), olanzapine (Zyprexa), aripiprazole (Abilify), asenapine (Saphris), iloperidone (Fanapt), haloperidol (Haldol), prochlorperazine (Compazine), chlorpromazine (Thorazine), clozapine (Clozaril), risperidone (Risperdal), quetiapine (Seroquel), and ziprasidone (Geodon)
  • antianxiety agents such as alprazolam (Xanax), diazepam (Valium), and lorazepam (Ativan)
  • CNS depressants (including alcohol)
  • MAO inhibitors including isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate)
  • tricyclic antidepressants such as trimipramine (Surmontil), amitriptyline (Elavil), nortriptyline (Pamelor, Aventyl), protriptyline (Vivactil), and clomipramine (Anafranil)

This is not a complete list of Lortab drug interactions. Ask your doctor or pharmacist for more information.

Lortab Precautions

Serious side effects have been reported with Lortab.

At high doses or in sensitive patients, hydrocodone may produce respiratory depression. Hydrocodone also affects the center that controls respiratory rhythm, and may produce irregular and periodic breathing. The respiratory depressant effects of hydrocodone may be exaggerated in the presence of head injury, other intracranial lesions or a preexisting increase in intracranial pressure. Hydrocodone may also produce adverse reactions that may obscure the clinical course of patients with head injuries.

Hydrocodone may obscure the diagnosis or clinical course of patients with acute abdominal conditions.

Hydrocodone suppresses the cough reflex; caution should be exercised when Lortab is used postoperatively and in patients with pulmonary disease.

Lortab should be used with caution in elderly or debilitated patients and those with severe impairment of hepatic or renal function, hypothyroidism, Addison's disease, prostatic hypertrophy or urethral stricture.

Lortab can cause drowsiness and dizziness. Do not drive or operate heavy machinery until you know how Lortab affects you.

Do not take Lortab if you are allergic to Lortab or to any of its ingredients or are allergic to any other opioid medication.

Lortab Food Interactions

Medications can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of Lortab, there are no specific foods that you must exclude from your diet when receiving this medication.

Inform MD

Before taking Lortab, tell your doctor about all of your medical conditions. Especially tell your doctor if you:

  • are allergic to Lortab or to any of its ingredients or are allergic to any other opioid medication
  • have or have ever had low blood pressure
  • have or have ever had difficulty urinating
  • have or have ever had seizures
  • have or have ever had thyroid disease
  • have or have ever had gall bladder disease
  • have or have ever had pancreas disease
  • have or have ever had liver disease
  • have or have ever had kidney disease
  • are pregnant or breastfeeding

Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements.

Lortab and Pregnancy

Tell your doctor if you are pregnant or plan to become pregnant.

The FDA categorizes medications based on safety for use during pregnancy. Five categories - A, B, C, D, and X - are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy.

Lortab falls into category C. There are no well-controlled studies that have been done in pregnant women. Lortab should be used during pregnancy only if the possible benefit outweighs the possible risk to the unborn baby.

Lortab and Lactation

Tell your doctor if you are breastfeeding or plan to breastfeed.

Acetaminophen, a component of Lortab, has been detected in human breast milk. It is not known if hydrocodone crosses into human milk. Because of the possibility for adverse reactions in nursing infants from Lortab, a choice should be made whether to stop nursing or to stop use of this medication. The importance of the drug to the mother should be considered.

Lortab Usage

Take Lortab exactly as prescribed. Lortab comes in a tablet form and is typically taken every 4 to 6 hours as needed for pain. Alcohol may intensify some of the side effects of this medication.

If you miss a dose, take the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and take your next dose at the regular time. Do not take 2 doses of Lortab at the same time.

Lortab Dosage

Take this medication exactly as prescribed by your doctor. Follow the directions on your prescription label carefully.

The dose your doctor recommends may be based on the following:

  • the condition being treated
  • other medical conditions you have
  • other medications you are taking
  • how you respond to this medication

The dosage of Lortab should be adjusted according to the severity of the pain and response of the patient. However, it is important to remember that tolerance to hydrocodone can develop with continued use and that the incidence of adverse effects is dose-related.

Lortab Overdose

If you take too much Lortab, call your healthcare provider or local Poison Control Center, or seek emergency medical attention right away.

If Lortab is administered by a healthcare provider in a medical setting, it is unlikely that an overdose will occur. However, if overdose is suspected, seek emergency medical attention.

Other Requirements

  • Store Lortab at room temperature.
  • Protect from exposure to light.
  • Keep this and all medicines out of the reach of children.

Lortab FDA Warning

HEPATOTOXICITY

Acetaminophen, a component of Lortab, has been associated with cases of acute liver failure, at times resulting in liver transplant and death. Most of the cases of liver injury are associated with the use of acetaminophen at doses that exceed 4,000 milligrams per day, and often involve more than one acetaminophen-containing product.