Entacapone

Entacapone treats symptoms of Parkinson's disease when used with levodopa and carbidopa. You may experience dizziness with this medication, so avoid standing up too fast to prevent falls.

Entacapone Overview

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Entacapone is a prescription medication that is used in combination with the medications levodopa and carbidopa to treat symptoms of Parkinson's disease. Entacapone belongs to a group of drugs called COMT inhibitors. It works to prevent the breakdown of levodopa and carbidopa and allows more of these medications to reach the brain. 

This medication comes in tablet form and is taken with every dose of levodopa and carbidopa, up to 8 times a day, with or without food. 

Common side effects of entacapone include diarrhea, nausea, change in the color of urine, and movements you cannot control.

Entacapone can also cause drowsiness and dizziness. Do not drive or operate heavy machinery until you know how entacapone affects you.

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Uses of Entacapone

Entacapone is a prescription medication that is used in combination with the medications levodopa and carbidopa to treat the symptoms of Parkinson's disease, a disorder of the nervous system that affects movement.

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

Entacapone Brand Names

Entacapone may be found in some form under the following brand names:

Entacapone Drug Class

Entacapone is part of the drug class:

Side Effects of Entacapone

Serious side effects have been reported with entacapone. See the "Entacapone Precautions" section.

Common side effects of entacapone include the following:

  • diarrhea
  • nausea
  • stomach pain
  • dizziness
  • drowsiness
  • movements you cannot control
  • change in the color of urine

This is not a complete list of entacapone side effects. Ask your doctor or pharmacist for more information.

Tell your doctor if you have any side effect that bothers you or that does not go away.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.