Azilect is used to treat Parkinson’s Disease. Tell your doctor about all medications you are taking. Dietary changes may be necessary when taking Azilect.

Azilect Overview


Azilect is a prescription medication used to treat Parkinson's disease. Azilect belongs to a group of drugs called monoamine oxidase (MAO) type B inhibitors. The exact way Azilect works for Parkinson's disease is unknown, but it is thought to work by increasing dopamine levels in the body. 

Azilect comes in tablet form and is usually taken by mouth, once daily, with or without food. 
Common side effects of Azilect include joint pain, depression, and flu syndrome.

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Azilect Cautionary Labels


Uses of Azilect

Azilect is a prescription medicine used to treat Parkinson's disease

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.


Azilect Drug Class

Azilect is part of the drug class:

Side Effects of Azilect

Common side effects of Azilect when taken alone are:

  • flu syndrome
  • joint pain
  • depression
  • indigestion

 When taken with levodopa common side effects include:

  • uncontrolled movements (dyskinesia)
  • accidental injury
  • weight loss
  • low blood pressure when standing
  • vomiting
  • anorexia
  • joint pain
  • abdominal pain
  • nausea
  • constipation
  • dry mouth
  • rash
  • abnormal dreams
  • fall

This is not a complete list of Azilect side effects. Ask your doctor or pharmacist for more information.

Azilect Interactions

Tell your doctor about all the medicines you take including prescription or non-prescription medicines, vitamins, or herbal supplements. Especially tell your doctor if you take:

  • meperidine
  • tramadol
  • methadol
  • propoxyphene
  • dextromethorphan (found in many non-prescription cough medicines)
  • other monoamine oxidase inhibitors (MAOIs)
  • St. John's wort
  • cyclobenzaprine
  • medicines for depression (antidepressants)
  • ciprofloxacin

This is not a complete list of Azilect drug interactions. Ask your doctor or pharmacist for more information.

Azilect Precautions

Serious side effects have occurred with Azilect when taken with antidepressant medicines. Tell your doctor if you are taking an antidepressant.

You should not take Azilect if you have moderate to severe liver disease.

You should not take more than 1 mg of Azilect per day. When taken in amounts greater than 1 mg per day, Azilect may cause a serious and possibly dangerous increase in blood pressure called hypertensive crisis.

Talk to your doctor about monitoring for skin cancer (melanoma) on a regular basis. People taking Azilect may have a higher risk of melanoma.

Azilect Food Interactions

Tyramine is a naturally occurring compound found in some cheeses and other foods that may cause dangerously high blood pressure in people taking monoamine oxidase inhibitors (MAOIs) like Azilect. You should avoid eating very large amounts of foods containing high amounts of tyramine such as aged cheeses, yogurt, tap beer, and fermented soy products. Some of the signs and symptoms of dangerously high blood pressure (hypertensive crisis) are:

  • severe headache
  • vision problems
  • confusion
  • stupor (mental numbness)
  • coma
  • seizures
  • chest pain
  • unexplained nausea or vomiting
  • stroke-like symptoms (sudden numbness or weakness - especially on one side of the body)

Get emergency medical help if you experience these symptoms.

Inform MD

Before receiving Azilect, tell your doctor if you are allergic to any of the ingredients found in Azilect.

Tell your doctor about all of your medical conditions including if you have liver disease. 

Tell your doctor if you are pregnant or breastfeeding.

Tell your doctor if you are taking, or are planning to take, prescription or non-prescription medicines, vitamins, or herbal supplements.

Azilect and Pregnancy

It is not known if Azilect will harm an unborn baby if taken during pregnancy. Azilect should be used during pregnancy only if the potential benefit justifies the potential risk to the unborn baby.

Azilect and Lactation

Azilect inhibits prolactin secretion and may inhibit breast milk secretion. It is not known if Azilect is excreted in human breast milk or if it will harm your baby.

Azilect Usage

Azilect comes as a tablet to be taken by mouth with or without food. It is usually taken once a day at around the same time. Take Azilect exactly as your doctor has prescribed it.  Do not stop taking Azilect suddenly as you may experience unpleasant symptoms. Your doctor will talk to you about slowly stopping Azilect to avoid these symptoms if you must stop taking it. If you miss a dose, don't double up, just take your next dose as scheduled.

Azilect Dosage

Azilect  is usually taken once daily by mouth, with or without food. Take Azilect exactly as it is prescribed by your doctor. Azilect has been shown to work when taken alone for symptom relief in early-stage Parkinson’s disease or taken with carbidopa/levodopa and other Parkinson’s disease medications when more relief is needed. The recommended doses are 0.5 or 1 mg daily.

Azilect Overdose

If you have taken too much Azilect seek emergency medical attention or call your local Poison Control Center right away.

Other Requirements

Store this medication at room temperature, away from excess heat and moisture. Keep this and all medicines out of the reach of children.