Dilaudid

Dilaudid relieves pain. Do not drink alcohol while taking this medication. May cause constipation.

Dilaudid Overview

Updated: 

Dilaudid is a prescription medication used to relieve pain. Dilaudid belongs to a group of drugs called narcotic analgesics. These work by changing the way that the brain and nervous system respond to pain.

This medication comes in oral solution and tablet forms and is taken up to 4 times a day.

This medication is also available in an injectable form to be given directly into a vein (IV), a muscle (IM), or under the skin (subcutaneous).

Common side effects of Dilaudid include nausea, vomiting, constipation, drowsiness, lightheadedness, anxiety, mood changes, rash, and itching. Dilaudid can also cause drowsiness and dizziness. Do not drive or operate heavy machinery until you know how Dilaudid affects you.

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  • Cough
  • Pain, Postoperative

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Dilaudid Cautionary Labels

precautionsprecautionsprecautions

Uses of Dilaudid

Dilaudid is a prescription medication used to relieve pain.

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

 

Manufacturer

Dilaudid Drug Class

Dilaudid is part of the drug class:

Side Effects of Dilaudid

Serious side effects have been reported with Dilaudid. See the “Dilaudid Precautions” section.

Oral:

Common side effects of oral Dilaudid include the following:

  • Nausea
  • Vomiting
  • Headache
  • Difficulty sleeping
  • Loss of appetite
  • Dry mouth
  • Lightheadedness
  • Heavy sweating
  • Muscle, back, or joint pain
  • Stomach pain
  • Anxiety
  • Flushing
  • Itching
  • Depression

Injectable:

Common side effects of Dilaudid injection include the following:

  • Nausea
  • Vomiting
  • Constipation
  • Drowsiness
  • Dizziness
  • Lightheadedness
  • Flushing
  • Mood changes
  • Itching
  • Dry Mouth

This is not a complete list of Dilaudid side effects. Ask your doctor or pharmacist for more information.

Tell your doctor if you have any side effect that bothers you or that does not go away.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Dilaudid Interactions

Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your doctor if you take:

  • Buprenorphine (Buprenex, Butrans, in Suboxone)
  • Butorphanol (Stadol)
  • Ipratropium (Atrovent)
  • Medications for glaucoma, irritable bowel disease, Parkinson's disease, ulcers, and urinary problems
  • Pentazocine (Talwin)

Also tell your doctor or pharmacist if you are taking any of the following medications or have stopped taking them within the past 2 weeks:

  • Isocarboxazid (Marplan)
  • Phenelzine (Nardil)
  • Selegiline (Eldepryl, Emsam, Zelapar)
  • Tranylcypromine (Parnate)

This is not a complete list of Dilaudid drug interactions. Ask your doctor or pharmacist for more information.

Dilaudid Precautions

Oral:

Serious side effects have been reported with oral Dilaudid including the following:

  • Rash
  • Hives
  • Swelling of the eyes, face, lips, tongue, mouth, throat, arms, hands, feet, ankles, or lower legs
  • Difficulty breathing or swallowing
  • Hoarseness
  • Seizures
  • Chest pain
  • Extreme drowsiness
  • Fainting

Injectable:

Serious side effects have been reported with Dilaudid injection including the following:

  • Slowed or stopped breathing
  • Rash
  • Hives
  • Swelling of the eyes, face, lips, tongue, mouth, throat, arms, hands, feet, ankles, or lower legs
  • Difficulty breathing or swallowing
  • Hoarseness
  • Seizures
  • Fainting

Dilaudid can cause dizziness and drowsiness. Do not drive or operate heavy machinery until you know how Dilaudid affects you.

Do not take Dilaudid if you:

  • are allergic to Dilaudid or to any of its ingredients
  • have respiratory depression
  • have acute, severe, or uncontrolled asthma

Dilaudid Food Interactions

Medications can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of Dilaudid, there are no specific foods that you must exclude from your diet when receiving this medication.

Do not drink alcohol or take products containing alcohol while taking Dilaudid.

Inform MD

Before taking Dilaudid, tell your doctor about all of your medical conditions. Especially tell your doctor if you:

  • are allergic to Dilaudid or to any of its ingredients
  • are allergic to sulfites or latex
  • have ever had a head injury or condition that damaged the brain
  • any condition that increases the pressure in your brain
  • kyphoscoliosis (curving of the spine that may cause breathing problems)
  • low blood pressure
  • hypothyroidism (condition in which the thyroid gland produces less hormone than normal)
  • lung disease such as chronic obstructive pulmonary disease (a group of diseases that affect the lungs and airways)
  • Addison's disease (condition in which the adrenal gland produces less hormone than normal)
  • seizures
  • delirium tremens (severe withdrawal symptoms that may occur in people who drank large amounts of alcohol over time and have stopped drinking)
  • urethral stricture (blockage of the tube that allows urine to leave the body)
  • an enlarged prostate (a male reproductive gland)
  • gallbladder disease
  • pancreatic disease
  • liver disease
  • kidney disease

Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements.

Dilaudid and Pregnancy

Tell your doctor if you are pregnant or plan to become pregnant.

The FDA categorizes medications based on safety for use during pregnancy. Five categories - A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy.

Dilaudid falls into category C. There are no well-controlled studies that have been done in pregnant women. Dilaudid should be used during pregnancy only if the possible benefit outweighs the possible risk to the unborn baby.

Dilaudid and Lactation

Tell your doctor if you are breastfeeding or plan to breastfeed.

Dilaudid has been detected in human breast milk. Because of the possibility for adverse reactions in nursing infants from Dilaudid, a choice should be made whether to stop nursing or to stop use of this medication. The importance of the drug to the mother should be considered.

Dilaudid Usage

Take Dilaudid exactly as prescribed.

Oral:

This medication comes in oral solution and tablet forms and is taken up to 4 times a day. 

Injectable:

This medication is also available in an injectable form to be given directly into a vein (IV), a muscle (IM), or under the skin (subcutaneous).

If you miss a dose, take the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and take your next dose at the regular time. Do not take two doses of Dilaudid at the same time.

Dilaudid Dosage

Take Dilaudid exactly as prescribed by your doctor. Follow the directions on your prescription label carefully.

The Dilaudid dose your doctor recommends will be based on the following:

  • the condition being treated
  • other medical conditions you have
  • other medications you are taking
  • how you respond to this medication

Oral:

The recommended dose range of Dilaudid (hydromorphone) oral solution for the treatment of pain is 2.5 to 10 mg every 3 to 6 hours.

The recommended dose range of Dilaudid (hydromorphone) tablets for the treatment of pain is 2 to 4 mg every 4 to 6 hours.

Injectable:

The recommended dose range of Dilaudid (hydromorphone) injection into a muscle or under the skin for the treatment of pain is 1 to 2 mg every 2 to 3 hours.

The recommended dose range of Dilaudid (hydromorphone) injection into a vein for the treatment of pain is 0.2 to 1 mg every 2 to 3 hours.

Dilaudid Overdose

If you take too much Dilaudid, call your healthcare provider or local Poison Control Center, or seek emergency medical attention right away.

If Dilaudid is administered by a healthcare provider in a medical setting, it is unlikely that an overdose will occur. However, if overdose is suspected, seek emergency medical attention.

Other Requirements

  • Store Dilaudid at room temperature.
  • Keep this and all medicines out of the reach of children.

Dilaudid FDA Warning

Oral:

WARNING: DILAUDID ORAL LIQUID AND DILAUDID TABLETS CONTAIN HYDROMORPHONE, WHICH IS A POTENT SCHEDULE II CONTROLLED OPIOID AGONIST. SCHEDULE II OPIOID AGONISTS, INCLUDING MORPHINE, OXYMORPHONE, OXYCODONE, FENTANYL, AND METHADONE, HAVE THE HIGHEST POTENTIAL FOR ABUSE AND RISK OF PRODUCING RESPIRATORY DEPRESSION. ALCOHOL, OTHER OPIOIDS AND CENTRAL NERVOUS SYSTEM DEPRESSANTS (SEDATIVE-HYPNOTICS) POTENTIATE THE RESPIRATORY DEPRESSANT EFFECTS OF HYDROMORPHONE, INCREASING THE RISK OF RESPIRATORY DEPRESSION THAT MIGHT RESULT IN DEATH.

WARNING: ADDICTION, ABUSE, AND MISUSE; LIFE-THREATENING RESPIRATORY DEPRESSION; ACCIDENTAL INGESTION; and NEONATAL OPIOID WITHDRAWAL SYNDROME

Hydromorphone hydrochloride extended-release tablets expose users to risks of addiction, abuse, and misuse, which can lead to overdose and death. Assess each patient’s risk before prescribing, and monitor regularly for development of these behaviors or conditions.

Serious, life-threatening, or fatal respiratory depression may occur. Monitor closely, especially upon initiation or following a dose increase. Instruct patients to swallow hydromorphone hydrochloride extended-release tablets whole to avoid exposure to a potentially fatal dose of hydromorphone.

Accidental ingestion of hydromorphone hydrochloride extended-release tablets, especially in children, can result in fatal overdose of hydromorphone.

Prolonged use of hydromorphone hydrochloride extended-release tablets during pregnancy can result in neonatal opioid withdrawal syndrome, which may be life-threatening if not recognized and treated. If opioid use is required for a prolonged period in a pregnant woman, advise the patient of the risk of neonatal opioid withdrawal syndrome and ensure that appropriate treatment will be available.

Injectable:

WARNING: RISK OF RESPIRATORY DEPRESSION, ABUSE, AND MEDICATION ERRORS DILAUDID-HP INJECTION IS FOR USE IN OPIOID-TOLERANT PATIENTS ONLY

Do not confuse DILAUDID-HP INJECTION with standard parenteral formulations of DILAUDID or other opioids, as overdose and death could result

Hydromorphone is a potent Schedule II opioid agonist. Schedule II opioid agonists have the highest potential for abuse and risk of producing respiratory depression. Ethanol, other opioids, and other central nervous system depressants can potentiate the respiratory-depressant effects of hydromorphone and increase the risk of adverse outcomes, including death.