Carglumic Acid

Carglumic Acid treats high levels of ammonia. Do not swallow tablets whole or crush tablets. Instead, each tablet should be dispersed in a minimum of 2.5 mL of water.

Carglumic Acid Genetic Information

Carglumic acid is used for the treatment of acute or chronic hyperammonemia. This occurs when levels of ammonia in your blood get too high. Some patients have a deficiency in an enzyme called N-acetylglutamate synthase (NAGS). NAGS is involved in activating a protein that is responsible for breaking down ammonia in the blood. In patients with a deficiency in NAGS, ammonia levels in the blood can become too high.

Carglumic acid is approved for the treatment of acute or chronic hyperammonemia in patients with NAGS deficiency.

Carglumic acid activates a protein that is responsible for breaking down ammonia in the blood, keeping your levels in check. Ammonia levels should continue to be monitored by your doctor, especially in an acute setting.

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Carglumic Acid Brand Names


Carglumic Acid may be found in some form under the following brand names:

Carglumic Acid Drug Class

Carglumic Acid is part of the drug class:

Carglumic Acid Interactions

This is not a complete list of Carglumic Aciddrug interactions. Ask your doctor or pharmacist for more information.

Carglumic Acid and Pregnancy

Tell your doctor if you are pregnant or plan to become pregnant.

The FDA categorizes medications based on safety for use during pregnancy. Five categories - A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy.

Carglumic Acid falls into category C:

In animal studies, pregnant animals were given this medication and had some babies born with problems. No well-controlled studies have been done in humans, though. Therefore, this medication may be used if the potential benefits to the mother outweigh the potential risks to the unborn child.


There are no well-controlled studies that have been done in pregnant women. Carglumic Acid should be used during pregnancy only if the possible benefit outweighs the possible risk to the unborn baby.


No studies have been done in animals, and no well-controlled studies have been done in pregnant women. Carglumic Acid should be given to a pregnant woman only if clearly needed.

Carglumic Acid Dosage

Take carglumic acid exactly as prescribed by your doctor. Follow the directions on your prescription label carefully.

The Carglumic Acid dose your doctor recommends will be based on the following (use any or all that apply):

  • the condition being treated
  • other medical conditions you have
  • other medications you are taking
  • how you respond to this medication
  • your weight
  • your height
  • your age
  • your gender

Carglumic Acid is available in the following doses:

  • Carglumic Acid 200 Mg Oral Tablet, Dispersible

Forms of Medication

Carglumic Acid is available in the following forms:

  • Oral Suspension