Clomiphene can also help men who have a low sperm count or who have poor sperm quality. When a man takes Clomid, it encourages his pituitary gland to make lutenizing hormone, which tells the testicles to produce more testosterone, and possibly more sperm. Men take clomiphene in cycles that last from three to six months. Clomiphene is less expensive and invasive than other fertility treatments, and can be a good first line of defense against infertility.