Nonsteroidal anti-inflammatory drugs, also known as NSAIDs, are a type of medication designed to REDUCE swelling and stiffness and RELIEVE pain. They can help treat everything from muscle soreness to arthritis. But these meds work best on joint pain that is ALSO paired with swelling or tenderness. The most well known NSAIDs are the over-the-counter versions--aspirin and ibuprofen, better known to you as Motrin and Advil--and naproxen, better known as Aleve. Stronger prescription versions are available as well. Anti-inflammatory drugs turn off your body's natural response to injury by blocking the enzymes that CAUSE inflammation and SEND pain signals to the brain. NEVER take NSAIDs on an empty stomach because of their potential to cause gastrointestinal upset and even bleeding. Have a snack or a glass of milk beforehand. Also, if you experience any side effects such as a rash, random bleeding and bruising, chest pain or stomach pain, stop taking them right away. And try NOT to take NSAIDS for more than 10 days unless you and your doctor have discussed the risks and benefits to you. Often your doctor can help you find another way to treat the pain. These meds are not for everyone. NSAIDs can cause dangerous complications when taken by people who have kidney or liver disease, ulcers, or uncontrolled diabetes. And, pregnant women should NOT take NSAIDs, either. If you have any health problems, it's best to double check with a health professional before taking any risks.