also referred to as 5-HTP, is used for depression. Can interact with many medications. Talk to your doctor before starting this supplement.
5-Hydroxytryptophan (5-HTP) is naturally produced by the body from the essential amino acid tryptophan.
5-HTP is used most often for depression.
5-HTP is thought to work by increasing levels of serotonin within the brain.
Common side effects of 5-HTP include nausea, vomiting, and diarrhea.
5-Hydroxytryptophan Cautionary Labels
5-HTP is used for depression, fibromyalgia, insomnia, binge eating associated with obesity, and chronic headaches.
5-HTP has not been proven effective for all of the uses listed above. 5-HTP may be used for other conditions. Ask your doctor or pharmacist for more information.
Side Effects of 5-Hydroxytryptophan
Common side effects of 5-HTP include:
This is not a complete list of 5-HTP side effects. Ask your doctor or pharmacist for more information.
Tell your doctor if you have any side effect that bothers you or that does not go away.
Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your doctor if you take:
- Selective serotonin reuptake inhibitor (SSRI) antidepressants such as fluoxetine (Prozac) or paroxetine (Paxil)
- Monoamine oxidase inhibitors (MAOIs) such as phenelzine (Nardil)
- Meperidine (Demerol)
- Dextromethorphan (Robitussin DM, others)
- Pentazocine (Talwin)
- Tramadol (Ultram)
It is possible that 5-HTP, when taken in combination with these drugs, can cause a condition known as serotonin syndrome. Serotonin syndrome is characterized by dizziness, fever, agitation, confusion, fast heartbeat, excessive sweating, flushing, shakiness, hallucinations, over-responsive reflexes, or upset stomach. Stop taking 5-HTP if you experience any of these symptoms and contact your healthcare provider.
Special precautions & warnings:
- Potential for development of serotonin syndrome exists when combined with selective serotonin reuptake inhibitor (SSRIs) or Monoamine oxidase inhibitors (MAOIs) and other drugs.
- Talk with your doctor or pharmacist before using 5-HTP if you are pregnant, breast-feeding, or trying to become pregnant.