No. Although the nasal spray flu vaccine (FluMist) contains weakened live viruses, it cannot cause the patient to get the flu (influenza).
According to the CDC, the weakened viruses are cold-adapted, which means they are designed to only cause infection at the cooler temperatures found within the nose. The viruses cannot infect the lungs or other areas where warmer temperatures exist.
Some children and young adults 2 years through 17 years of age have reported experiencing mild reactions after getting the nasal spray flu vaccine, including runny nose, nasal congestion or cough, chills, tiredness/weakness, sore throat and headache.
Some adults 18 years through 49 years of age have reported runny nose or nasal congestion, cough, chills, tiredness/weakness, sore throat and headache. These side effects are mild and short-lasting, especially when compared to symptoms of influenza infection.
The nasal spray is approved for use in people 2 through 49 years of age. Some people with certain medical conditions should not receive the nasal spray vaccine. Your pharmacist and doctor can help you decide which flu vaccine is right for you. How to Stay Healthy During Flu Season