Zyrtec D treats seasonal allergies and nasal congestion. If you have high blood pressure, this medication may not be safe to use. Ask your doctor before taking it.

Zyrtec-D Overview


Zyrtec-D is an over-the-counter (OTC) medication used for the treatment of hay fever, seasonal allergies, hives, and nasal congestion in adults and children 12 years of age and older. 

It is a single product containing 2 ingredients: Cetirizine and Pseudoephedrine.

Cetirizine belongs to a group of drugs called antihistamines. These works by blocking the action of histamine, a substance in the body that causes allergic symptoms. Pseudoephedrine belongs to a group of drugs called nasal decongestant. These work by causing narrowing of the blood vessels in the nasal passages.

This medication comes as an extended-release tablet to take by mouth, and is usually taken once to twice a day with or without food. Do not chew, divide, or break Zyrtec extended-release tablets. Swallow extended release tablets whole.

Common side effects include drowsiness, headaches, increase in blood pressure, and dry mouth. Do not drive or operate heavy machinery until you know how Zyrtec affects you.


Patient Ratings for Zyrtec-D

How was your experience with Zyrtec-D?

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What are you taking Zyrtec-D for?

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  • Other
  • Asthma
  • Common Cold
  • Rhinitis, Allergic, Perennial
  • Sinusitis
  • Urticaria

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  • A couple weeks
  • A month or so
  • A few months
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Zyrtec-D consists of multiple generic medications. The generic medications are listed below.


For more information on this medication choose from the list of selections below.


For more information on this medication choose from the list of selections below.

Zyrtec-D Drug Class

Zyrtec-D is part of the drug class: