TriNessa

TriNessa prevents pregnancy. Many medications, including some antibiotics and supplements, can cause TriNessa to not work. Ask your pharmacist or doctor before taking any other medications.

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Pharmacist Trey Robinson, PharmD overviews the uses and common side effects of TriNessa
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Pharmacist Trey Robinson, PharmD overviews the uses and common side effects of TriNessa
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TriNessa Overview

Reviewed: June 3, 2013
Updated: 

TriNessa is a prescription birth control medication used to prevent pregnancy. It can also be used to treat moderate acne in females at least 15 years old who have started to have menstrual periods. It contains two hormones, norgestimate and ethinyl estradiol, which belong to a group of drugs called hormonal contraceptives. These hormones prevent pregnancy by stopping ovulation and by altering cervical mucus and the lining of the uterus.

This medication comes in tablet form. It is taken once daily, with or without food.

Common side effects include nausea, breast tenderness, and vaginal bleeding between menstrual periods.

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TriNessa Cautionary Labels

precautionsprecautionsprecautionsprecautionsprecautions

Uses of TriNessa

TriNessa is a prescription birth control medication used:

  • to prevent pregnancy
  • to treat acne in females at least 15 years of age who have started having menstrual periods
 
This medication may be prescribed for other uses.  Ask your doctor or pharmacist for more information.

Manufacturer

TriNessa Drug Class

TriNessa is part of the drug class:

Side Effects of TriNessa

Serious side effects have been reported with TriNessa. See "Drug Precautions" section.

Common side effects include:
  • nausea
  • spotting or bleeding between menstrual periods
  • headache
  • change in menstrual flow
  • swelling of the fingers or ankles
  • breast tenderness, enlargement, or secretion
  • weight changes
  • difficulty wearing contact lenses

​This is not a complete list of TriNessa side effects. Ask your doctor or pharmacist for more information.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

TriNessa Interactions

Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your doctor if you take:

  • antibiotics such as rifampin
  • antifungals such as griseofulvin, itraconazole, and ketoconazole
  • barbiturates such as phenobarbital
  • seizure medications such as phenytoin (Dilantin), carbamazepine (Tegretol), oxcarbazepine (Trileptal), topiramate (Topamax), and lamotrigine (Lamictal)
  • certain anti-HIV medications called protease inhibitors
  • St. John's Wort
  • atorvastatin (Lipitor)

This is not a complete list of TriNessa interactions. Ask your doctor or pharmacist for more information.

TriNessa Precautions

Serious side effects have been reported with TriNessa including:

  • Blood clots, heart attack and stroke - Tell your healthcare provider right away if you have some or all of the following:
    • shortness of breath
    • sharp or crushing chest pain
    • weakness or numbness in an arm or leg
    • slurring of speech
    • coughing of blood
    • pain in the calf
    • sudden severe headache or vomiting
    • dizziness or fainting
  • Hypertension - Have your blood pressure monitored by your doctor closely if taking TriNessa, especially if you have a history of hypertension or are taking medications to treat hypertension
  • Lipid disorders - Women who are being treated for hyperlipidemia (high blood fat/cholesterol) should be monitored closely, as steroids can elevate lipid levels.
  • Breast, ovarian, or uterine cancer - Tell your healthcare provider right away if you detect a lump in the breast.  
  • Liver problems - Tell your healthcare provider right away if you have some or all of the following:
    • severe pain or tenderness in the stomach area
    • yellowing of the skin or eyeballs
  • Severe depression - Tell your healthcare provider right away if you have some or all of the following:
    • difficulty sleeping
    • weakness, lack of energy, fatigue
    • change in mood
  • Eye conditions - Tell your healthcare provider right away if you have some or all of the following:
    • unexplained partial or complete loss of vision
    • double vision
    • bulging of the eyes
  • Severe migraine headaches - Tell your healthcare provider right away if you experience recurrent or persistent headaches.
 
TriNessa does not protect against HIV infection or other sexually-transmitted diseases and is not intended for use in emergency contraception.
 
Do not take TriNessa if you:
  • have a history of heart attack or stroke
  • have blood clots in the legs, lungs, or eyes
  • have a history of blood clots in the deep veins of your legs
  • have chest pain (angina pectoris)
  • have or have had cerebral vascular or coronary artery disease
  • have disease of the heart valves with complications
  • have severe hypertension (very high blood pressure)
  • have diabetes with blood vessel involvement
  • have headaches with focal neurological symptoms (movement disorders affecting a specific region of the body, such as the left arm or right leg)
  • have had a major surgery requiring a long period of inactivity
  • have, may have, or have had cancer of the breast
  • have cancer of the lining of the uterus or other estrogen-dependent cancer
  • have undiagnosed abnormal genital bleeding
  • have jaundice (yellowing of the skin or eyes)
  • have liver disease with abnormal liver function
  • have tumors of the liver
  • are or may be pregnant
  • are allergic to any component of TriNessa

TriNessa Food Interactions

Medicines can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods.  In the case of TriNessa there are no specific foods that you must exclude from your diet when receiving TriNessa.

 

Inform MD

Before taking TriNessa, tell your doctor about all of your medical conditions. Especially tell your doctor if you have or have had:

  • diabetes
  • high blood pressure
  • nodules in the breast, fibrocystic disease of the breast, or abnormal breast x-ray or mammogram
  • high blood fat or cholesterol levels
  • migraine or other headaches
  • seizures (epilepsy)
  • depression
  • gall bladder, liver, heart, or kidney disease
  • irregular menstrual periods

Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements.

TriNessa and Pregnancy

Tell your doctor if you are pregnant or plan to become pregnant.

The FDA categorizes medications based on safety for use during pregnancy.  Five categories - A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy.
 
TriNessa falls into category X.  This medication should not be used during pregnancy as it has the potential to cause miscarriage.  

TriNessa and Lactation

Tell your doctor if you are breastfeeding or plan to breastfeed.  

You should not take TriNessa if you are breastfeeding. It may be excreted in your breast milk and may harm your nursing child.

TriNessa Usage

Take TriNessa exactly as prescribed.

Take TriNessa tablet once a day, every day, at the same time every day.

TriNessa Dosage

Take TriNessa exactly as prescribed by your doctor. Follow the directions on your prescription label carefully. 

 

TriNessa Overdose

If you take too much TriNessa, call your healthcare provider or local Poison Control Center, or seek emergency medical attention right away.

Other Requirements

  • Store TriNessa at room temperature between 59° and 86°F and protect it from light.
  • Keep this and all medicines out of the reach of children.

TriNessa FDA Warning

Cigarette smoking increases the risk of serious cardiovascular side effects from oral contraceptive use. This risk increases with age and with heavy smoking (15 or more cigarettes per day) and is quite marked in women over 35 years of age. Women who use oral contraceptives such as TriNessa should be strongly advised not to smoke.