Trientine is a prescription medication used to treat Wilson's disease. It helps to remove excess copper from the body. Take trientine on an empty stomach.

Trientine Overview

Reviewed: October 14, 2013

Trientine is a prescription medication that is used to treat Wilson's disease.

Trientine belongs to a group of drugs called chelating agents, which help by binding excess heavy metals and increasing the removal of the metals from the body.

Specifically, it can be used to remove the excess copper that is built up in patients with Wilson's disease

This medication comes in capsule form and is typically taken up to four times a day, on an empty stomach (take with plain water only). Take Syprine one hour before a meal or 2 hours after a meal. In addition, take at least 1 hour apart from any other drug, food, or milk.

Swallow capsules whole with water. Do not open or chew capsules.

Common side effects of trientine include iron deficiency, muscle spasms, muscle contractions, and skin irritation.

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Trientine Brand Names

Trientine may be found in some form under the following brand names:

Trientine Drug Class

Trientine is part of the drug class:

Side Effects of Trientine

Serious side effects have been reported with trientine. See the “Drug Precautions” section.

Common side effects of trientine include iron deficiency, muscle spasms, and skin irritation.

This is not a complete list of trientine side effects. Ask your doctor or pharmacist for more information.

Tell your doctor if you have any side effect that bothers you or that does not go away.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.