Trental

Trental reduces the symptoms of intermittent claudication which is pain in the legs when walking due to narrowing of blood vessels. It may take up to 8 weeks to feel a benefit.

Trental Overview

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Trental is a prescription medication used to reduce the symptoms of intermittent claudication (pain in the legs when walking due to narrowing of blood vessels). Trental belongs to a group of drugs called methylxanthine derivatives, which improve blood flow by decreasing the thickness of blood.

This medication comes in tablet form and is usually taken 3 times a day, with meals.

Common side effects of Trental include upset stomach, vomiting, gas, and headache. Trental can also cause dizziness. Do not drive or operate heavy machinery until you know how Trental affects you.

 

Patient Ratings for Trental

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What are you taking Trental for?

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  • Other
  • Brain Ischemia
  • Diabetic Angiopathies
  • Diabetic Neuropathies
  • Gangrene
  • Impotence, Vasculogenic
  • Intermittent Claudication
  • Malaria, Cerebral
  • Stroke
  • Thrombosis
  • Vasculitis

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  • A month or so
  • A few months
  • A year or so
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Trental Cautionary Labels

precautionsprecautionsprecautionsprecautions

Uses of Trental

Trental is a prescription medication used to reduce the symptoms of intermittent claudication (pain in the legs when walking due to narrowing of blood vessels).

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

Manufacturer

Trental Drug Class

Trental is part of the drug class:

Side Effects of Trental

Serious side effects have been reported with Trental. See the “Drug Precautions” section.

Common side effects include:

  • upset stomach
  • vomiting
  • gas
  • dizziness
  • headache
  • chest pain
  • fast heartbeat

This is not a complete list of Trental side effects. Ask your doctor or pharmacist for more information.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Trental Interactions

Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your doctor if you take:

  • anticoagulants or platelet aggregation inhibitors, especially warfarin (Coumadin)
  • drugs that contain theophylline
  • drugs that contain captopril (Capoten, Capozide) or nifedipine (Adalat, Adalat CC, Afeditab CR, Procardia, Procardia XL)

This is not a complete list of Trental drug interactions. Ask your doctor or pharmacist for more information.

Trental Precautions

Serious side effects have been reported with Trental including the following:

  • chest pain
  • fast heartbeat

Trental can cause dizziness and drowsiness. Do not drive or operate heavy machinery until you know how this medication affects you.

Do not take Trental if you:

  • are allergic to Trental or to any of its ingredients or to other methylxanthine derivatives, including caffeine, theophylline, and theobromine
  • have had a recent cerebral and/or retinal hemorrhage

Trental Food Interactions

Medications can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of Trental, there are no specific foods that you must exclude from your diet when receiving this medication.

Inform MD

Before taking Trental, tell your doctor about all of your medical conditions. Especially tell your doctor if you:

  • are allergic to Trental or to any of its ingredients or to other methylxanthine derivatives, including caffeine, theophylline, and theobromine
  • have had a recent cerebral and/or retinal hemorrhage
  • have or have had kidney disease
  • are having surgery, including dental surgery
  • are pregnant or plan to become pregnant
  • are breastfeeding or plan to breastfeed

Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements.

Trental and Pregnancy

Tell your doctor if you are pregnant or plan to become pregnant.

The FDA categorizes medications based on safety for use during pregnancy. Five categories - A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy.

Trental falls into category C. In animal studies, pregnant animals were given this medication and had some babies born with problems. No well-controlled studies have been done in humans, though. Therefore, this medication may be used if the potential benefits to the mother outweigh the potential risks to the unborn child.

Trental and Lactation

Tell your doctor if you are breastfeeding or plan to breastfeed.

Trental has been detected in human breast milk. Because of the possibility for adverse reactions in nursing infants from Trental, a choice should be made whether to stop nursing or to stop use of this medication. The importance of the drug to the mother should be considered.

Trental Usage

Take Trental exactly as prescribed.

Trental comes in tablet form and is usually taken three times every day.

Take with meals to avoid an upset stomach.

Do not chew, divide, or break Trental tablets. Swallow tablets whole.

If you miss a dose, take the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and take your next dose at the regular time. Do not take two doses of Trental at the same time.

Trental Dosage

Take Trental exactly as prescribed by your doctor. Follow the directions on your prescription label carefully.

The Trental dose your doctor recommends will be based on the following:

  • the condition being treated
  • other medical conditions you have
  • other medications you are taking
  • how you respond to this medication
  • your age

The recommended dose range for Trental (pentoxifylline) is 400 mg three times a day.

Trental Overdose

If you take too much Trental, call your healthcare provider or local Poison Control Center, or seek emergency medical attention right away.

Other Requirements

  • Store Trental at room temperature. Temperature may vary between 15-30°C (59-86°F).
  • Store Trental away from excess heat and moisture. Do not store it in the bathroom.
  • Keep this and all medicines out of the reach of children.