Tradjenta

Tradjenta Overview

Tradjenta (generic: linagliptin) is a prescription medication used to treat type 2 diabetes in adults.  Tradjenta belongs to a group of drugs called dipeptidyl peptidase-4 (DPP-4) inhibitors, which help lower blood sugar levels by regulating the amount of insulin released.

This medication comes in tablet form and is taken once a day, with or without food.

Common side effects of Tradjenta include stuffy nose, sore throat, and low blood sugar levels.

Uses of Tradjenta

Tradjenta is a prescription medicine used to treat type 2 diabetes in adults.  Tradjenta helps to lower blood sugar along with diet and exercise.

This medication may be prescribed for other uses.  Ask your doctor or pharmacist for more information.

Side Effects of Tradjenta

Tradjenta may cause serious side effects, including:

  • low blood sugar (hypoglycemia). If you take Tradjenta with another medicine that can cause low blood sugar, such as a sulfonylurea, your risk of getting low blood sugar is higher. The dose of your sulfonylurea medicine may need to be lowered while you take Tradjenta. Signs and symptoms of low blood sugar may include:
    • headache
    • drowsiness
    • weakness
    • dizziness
    • confusion
    • irritability
    • hunger
    • fast heart beat
    • sweating
    • feeling jittery

The most common side effects of Tradjenta include stuffy or runny nose and sore throat.

Tell your doctor if you have any side effect that bothers you or that does not go away.

These are not all the possible side effects of Tradjenta. For more information, ask your doctor or pharmacist.

Tradjenta Interactions

Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. 

Tradjenta may affect the way other medicines work, and other medicines may affect how Tradjenta works.

Especially tell your doctor if you take

  • other medicines that can lower your blood sugar
  • rifampin (Rifadin, Rimactane, Rifater, Rifamate), an antibiotic that is used to treat tuberculosis 

Ask your doctor or pharmacist for a list of these medicines if you are not sure if your medicine is one that is listed above.

Know the medicines you take. Keep a list of them and show it to your doctor and pharmacist when you get a new medicine.

Tradjenta Precautions

Do not take Tradjenta if you are allergic to linagliptin or any of the ingredients in Tradjenta. 

Symptoms of a serious allergic reaction to Tradjenta are:

  • rash
  • raised red patches on your skin (hives)
  • swelling of your face, lips, and throat that may cause difficulty breathing or swallowing

Tradjenta Food Interactions

Follow dietary (food) recommendations made by your doctor and dietitian which should include a healthy diet. Skipping meals should be avoided as this can cause problems maintaining blood sugar control. There are no specific foods to avoid while using Tradjenta.

Inform MD

Before you take Tradjenta, tell your doctor if you:

  • have any other medical conditions
  • are pregnant or planning to become pregnant. It is not known if Tradjenta will harm your unborn baby. If you are pregnant, talk with your doctor about the best way to control your blood sugar while you are pregnant.
  • are breastfeeding or plan to breastfeed. It is not known if Tradjenta passes into your breast milk. Talk with your doctor about the best way to feed your baby if you take Tradjenta. 

Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. 

Tradjenta and Pregnancy

Tell your doctor if you are pregnant or planning to become pregnant. It is not known if Tradjenta will harm your unborn baby. If you are pregnant, talk with your doctor about the best way to control your blood sugar while you are pregnant.

Tradjenta and Lactation

Tell your doctor if you are breastfeeding or plan to breastfeed. It is not known if Tradjenta passes into your breast milk. Talk with your doctor about the best way to feed your baby if you take Tradjenta. 

Tradjenta Usage

  • Take Tradjenta 1 time each day exactly as your doctor tells you to take it.
  • Talk with your doctor if you do not understand how to take Tradjenta.
  • Your doctor will tell you when to take Tradjenta.
  • Take Tradjenta with or without food.
  • If you miss a dose, take it as soon as you remember. If you do not remember until it is time for your next dose, skip the missed dose and go back to your regular schedule. Do not take two doses of Tradjenta at the same time.
  • Your doctor may tell you to take Tradjenta along with other diabetes medicines. Low blood sugar can happen more often when Tradjenta is taken with certain other diabetes medicines. 
  • If you take too much Tradjenta, call your doctor or Poison Control Center at 1-800-222-1222 or go to the nearest hospital emergency room right away.
  • When your body is under some types of stress, such as fever, trauma (such as a car accident), infection, or surgery, the amount of diabetes medicine that you need may change. Tell your doctor right away if you have any of these conditions and follow your doctor's instructions.
  • Check your blood sugar as your doctor tells you to.
  • Stay on your prescribed diet and exercise program while taking Tradjenta.
  • Talk to your doctor about how to prevent, recognize and manage low blood sugar (hypoglycemia), high blood sugar (hyperglycemia), and complications of diabetes.
  • Your doctor will check your diabetes with regular blood tests, including your blood sugar levels and your hemoglobin A1C.

Tradjenta Dosage

Take Tradjenta exactly as prescribed. Follow the directions on your prescription label carefully.

The recommended dose of Tradjenta is 5 mg once daily.

Tradjenta Overdose

If you take too much Tradjenta, call your local Poison Control Center or seek emergency medical attention right away.

Forms of Tradjenta

Tradjenta is available as 5 mg tablets.

Active Ingredient: linagliptin

Inactive Ingredients: mannitol, pregelatinized starch, corn starch, copovidone, and magnesium stearate. The film coating contains the following inactive ingredients: hypromellose, titanium dioxide, talc, polyethylene glycol, and red ferric oxide.

Other Requirements

Store Tradjenta at 59°F to 86°F (15°C to 30°C).

Keep Tradjenta and all medicines out of the reach of children.

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Reviewed by: 
Beth Bolt, RPh
Review Date: 
August 20, 2012

Last Updated:
March 1, 2013