Rifapentine treats active and latent tuberculosis. May produce a red-orange discoloration of bodily fluids.

Rifapentine Overview


Rifapentine is a prescription medication used to treat active and latent tuberculosis. Rifapentine belongs to a group of medications called antibiotics which work by killing or slowing the growth of bacteria that cause infections.

Rifapentine is available as a tablet and is usually taken 1 to 2 times per week, with food. The number of times a week you take your medication will depend on what point of therapy you are at and it you are treating active or latent tuberculosis.

Common side effects of rifapentine include change in blood counts, joint pain, headache, vomiting, and nausea.

Patient Ratings for Rifapentine

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  • Other
  • Mycobacterium Infections
  • Tuberculosis, Pulmonary

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  • A month or so
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Rifapentine Cautionary Labels


Uses of Rifapentine

Rifapentine is used to treat active and latent tuberculosis caused by Mycobacterium tuberculosis. Rifapentine will be given with another anti-tuberculosis medication.

This medication may be prescribed for other uses. Contact your doctor or pharmacist for more information.

Rifapentine Brand Names

Rifapentine may be found in some form under the following brand names:

Rifapentine Drug Class

Rifapentine is part of the drug class:

Side Effects of Rifapentine

Serious side effects have been reported with rifapentine. See "Rifapentine Precautions" section.

Common side effects of rifapentine include:

  • decreased blood cell counts
  • increase in liver function test
  • joint pain
  • headache
  • vomiting
  • nausea
  • diarrhea
  • rash
  • itching

This is not a complete list of rifapentine side effects. Ask your doctor or pharmacist for more information.

Tell your doctor if you have any side effect that bothers you or that does not go away.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.