Rabies, Inactivated, Whole Virus

is a vaccine given to prevent rabies. Is it given for pre-exposure and post-exposure protection.

Rabies, Inactivated, Whole Virus Overview

Updated: 

Rabies, Inactivated, Whole Virus is a vaccine used to prevent rabies. It is used for people who have a potential to be exposed to the virus, as well as for people who have been exposed to the virus.

It is available in an injectable form to be given directly into the muscle (IM) by a healthcare professional.

Common side effects include nausea, headache, and soreness, redness, or swelling at the injection site.

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Uses of Rabies, Inactivated, Whole Virus

Rabies, Inactivated, Whole Virus is a vaccine used to prevent rabies. It is used for people who have a potential to be exposed to the virus, as well as for people who have been exposed to the virus. It is approved for use in people of all ages.

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

Rabies, Inactivated, Whole Virus Brand Names

Rabies, Inactivated, Whole Virus may be found in some form under the following brand names:

Rabies, Inactivated, Whole Virus Drug Class

Rabies, Inactivated, Whole Virus is part of the drug class:

Side Effects of Rabies, Inactivated, Whole Virus

Serious side effects have been reported with this vaccine. See the "Rabies, Inactivated, Whole Virus Precautions" section.

Common side effects include the following:

  • soreness, redness, swelling, or itching at the injection site
  • headache
  • nausea
  • abdominal pain
  • muscle aches
  • dizziness
  • hives
  • pain in the joints
  • fever

This is not a complete list of side effects. Ask your doctor or pharmacist for more information.

Tell your doctor if you have any side effect that bothers you or that does not go away.

Call your doctor for medical advice about side effects. You may report side effects to VAERS at 1-800-822-7967.

Rabies, Inactivated, Whole Virus Interactions

Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your doctor if you take:

  • other vaccines
  • medications that suppress the immune system
    • radiation therapy
    • antimalarial drugs
    • corticosteroids

This is not a complete list of drug interactions. Ask your doctor or pharmacist for more information.

Rabies, Inactivated, Whole Virus Precautions

Serious side effects have been reported with this vaccine including the following:

  • severe allergic reaction (anaphylaxis)
  • bronchospasm
  • urticaria (rash)
  • edema
  • neuroparalysis
  • encephalitis
  • meningitis
  • transient paralysis
  • Guillain-Barre syndrome
  • multiple sclerosis
  • vertigo
  • visual disturbance
  • palpitations
  • flushing

Do not receive this vaccine if you are allergic to this vaccine or to any of its ingredients

Rabies, Inactivated, Whole Virus Food Interactions

Medications and vaccines can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of this vaccine, there are no specific foods that you must exclude from your diet when receiving this vaccine.

Inform MD

Before receiving this vaccine, tell your doctor about all of your medical conditions. Especially tell your doctor if you:

  • are allergic to this vaccine or to any of its ingredients
  • are pregnant or plan to become pregnant
  • are breastfeeding or plan to breastfeed
  • have a weakened immune system because of:
    • HIV/AIDS or another disease that affects the immune system
    • treatment with drugs that affect the immune system such as steroids
    • cancer, or cancer treatment with radiation or drugs

If you have a minor illness, such as a cold, you can be vaccinated. If you are moderately or severely ill, you should probably wait until you recover before getting a routine (non-exposure) dose of rabies vaccine. If you have been exposed to the rabies virus, you should get the vaccine regardless of any other illnesses you may have.

Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements.

Rabies, Inactivated, Whole Virus and Pregnancy

Tell your doctor if you are pregnant or plan to become pregnant.

The FDA categorizes medications and vaccines based on safety for use during pregnancy. Five categories - A, B, C, D, and X are used to classify the possible risks to an unborn baby when a medication or vaccine is used during pregnancy.

Rabies, Inactivated, Whole Virus falls into category C. No studies have been done in animals, and no well-controlled studies have been done in pregnant women. Rabies, Inactivated, Whole Virus should be given to a pregnant woman only if potential benefits outweigh potential risks.

If there is substantial risk of exposure to rabies, pre-exposure prophylaxis may also be indicated during pregnancy. Because of the potential consequences of inadequately treated rabies exposure, pregnancy is not considered a contraindication to post-exposure prophylaxis.

Rabies, Inactivated, Whole Virus Usage

Receive this vaccine exactly as prescribed.

This vaccine is available in an injectable form to be given directly into the muscle (IM) by a healthcare professional.

Rabies, Inactivated, Whole Virus Dosage

Use this vaccine exactly as prescribed by your healthcare provider.

The dose your doctor recommends will be based on your potential for exposure to the rabies virus, or the likelihood that you have been exposed to the virus, and your rabies vaccine history.

A single dose for adults, children, and infants is 1ml given intramuscularly (IM). 

Pre-exposure Dosage

  • Primary immunization: 3 injections of 1ml each are recommended; one on day 0, one on day 7, and one on either day 21 or 28
  • Booster immunization: individual booster dose is 1ml, given to people who have received previous rabies immunization and remain at increased risk of rabies exposure

Post-exposure Dosage

  • Immunization should begin as soon as possible after exposure. 
  • A complete course consists of a total of 5 injections of 1ml each: one injection on each of days 0, 3, 7, 14, and 28 in conjunction with HRIG (Human Rabies Immunoglobulin) on day 0.

Post-exposure Prophylaxis of Previously Immunized Persons

  • When rabies exposure occurs in a previously vaccinated person, that person should receive two doses (1ml each): one immediately and one 3 days later. Human Rabies Immunoglobulin should not be given in these cases.

Rabies, Inactivated, Whole Virus Overdose

Rabies, Inactivated, Whole Virus is administered by a healthcare provider in a medical setting, so it is unlikely that an overdose will occur. However, if overdose is suspected, seek emergency medical attention.

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