Probuphine is a maintenance treatment of opioid dependence. It is available as an implant placed under the skin of the upper arm and provides a constant amount of medication or six months.

Probuphine Overview

Reviewed: May 31, 2016

Probuphine is a prescription medication used as a maintenance treatment of opioid dependence. Probuphine belongs to a group of drugs called opioid partial agonist-antagonists. These work to treat dependence, because they produce similar effects to opioids.

It is available as an implantable rod that is placed under the skin of the upper arm by a healthcare professional. 

Common side effects include implant-site pain, itching, and redness as well as headache. 

Patient Ratings for

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  • Heroin Dependence
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Probuphine Cautionary Labels


Probuphine Drug Class

Probuphine is part of the drug class: