Vytorin is a prescription medication used in combination with diet and exercise to treat high cholesterol. It is also used to lower cholesterol in people with homozygous familial hypercholesterolemia (HoFH, a hereditary disorder that causes high cholesterol levels).

This medication is a single tablet containing two prescription medicines, ezetimibe and simvastatin. Ezetimibe belongs to a group of drugs called cholesterol absorption inhibitors, which block the absorption of cholesterol from the intestines. Simvastatin belongs to a group of drugs called HMG-CoA reductase inhibitors, also known as statins, which block an enzyme in the body called HMG-CoA reductase. This is a major enzyme involved in making cholesterol in the body.

This medication comes in tablet form and is usually taken once daily, in the evening. Vytorin can be taken with or without food.

Common side effects of Vytorin include headache, muscle pain, and diarrhea.