Vimovo is a prescription medication used to treat the pain and inflammation associated with osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. It is also used to prevent ulcers.
It comes as a single tablet containing 2 medications, esomeprazole and naproxen. Esomeprazole belongs to a group of drugs called proton pump inhibitors which work by reducing acid production in the stomach. Naproxen is a nonsteroidal anti-inflammatory drug (NSAID) that works by blocking the production of substances that cause inflammation.
Vimovo is taken twice daily, at least 30 minutes before a meal. Swallow tablets whole.
Common side effects include indigestion, stomach pain, stomach ulcers, and diarrhea.
Cardiovascular Risk
Non-Steroidal Anti-inflammatory Drugs (NSAIDs), a component of Vimovo, may cause an increased risk of serious cardiovascular thrombotic events, myocardial infarction, and stroke, which can be fatal. This risk may increase with duration of use. Patients with cardiovascular disease or risk factors for cardiovascular disease may be at greater risk.
Vimovo is contraindicated for the treatment of peri-operative pain in the setting of coronary artery bypass graft (CABG) surgery.
Gastrointestinal Risk
NSAIDs, including naproxen, a component of Vimovo, cause an increased risk of serious gastrointestinal adverse events including bleeding, ulceration, and perforation of the stomach or intestines, which can be fatal. These events can occur at any time during use and without warning symptoms. Elderly patients are at greater risk for serious gastrointestinal events.
