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Sylatron

Sylatron is a prescription medication used to prevent malignant melanoma (a kind of skin cancer) from coming back after it has been removed by surgery. Sylatron belongs to a group of drugs called interferons. The way Sylatron treats malignant melanoma is unknown.

This medication comes in an injectable form to be given just under the skin once a week. 
 
Common side effects of Sylatron include flu-like symptoms (fever, headaches, chills), tiredness, appetite problems, and redness or swelling at the injection site. 
 

WARNING: DEPRESSION AND OTHER NEUROPSYCHIATRIC DISORDERS

The risk of serious depression, with suicidal ideation and completed suicides, and other serious neuropsychiatric disorders are increased with alpha interferons, Sylatron Permanently discontinue peginterferon alfa-2b in patients with persistently severe or worsening signs or symptoms of depression, psychosis, or encephalopathy. These disorders may not resolve after stopping Sylatron.

Melanoma [1] Skin Cancer [2] Cancer [3]
Citation: 
"Sylatron," DailyMed: Current Medication Information; U.S. National Library of Medicine [4]
http://www.rxwiki.com/sylatron [5]
Peginterferon Alfa-2b [6]
Rx Company Link: 
Merck Sharp & Dohme Corp. [7]
RxNorm ATC Ref: 
interferon [8]
Contributor: 
Teresa Brucker, Pharm.D [9] Eric Ho, Pharm.D [10] Anyssa Garza, PharmD [11]
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published_note: 
RX Label Type: 
Long Title: 
Sylatron prevents melanoma from coming back after surgery. Inject this medication at bedtime to help reduce flu-like symptoms. Your doctor may also recommend Tylenol to reduce flu-like symptoms.
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Source URL (retrieved on 06/09/2026 - 08:27): https://www.rxwiki.com/sylatron

Links:
[1] https://www.rxwiki.com/conditions/melanoma
[2] https://www.rxwiki.com/conditions/skin-cancer
[3] https://www.rxwiki.com/conditions/cancer
[4] http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=738947e9-b8ae-4592-8c10-5e5bdcd451b9
[5] http://www.rxwiki.com/sylatron
[6] https://www.rxwiki.com/peginterferon-alfa-2b
[7] https://www.rxwiki.com/merck-sharp-dohme-corp
[8] https://www.rxwiki.com/rxnorm-atc/interferon
[9] https://www.rxwiki.com/users/teresa-brucker-pharmd
[10] https://www.rxwiki.com/users/eric-ho-pharmd
[11] https://www.rxwiki.com/users/anyssa-garza-pharmd