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Jakafi

Jakafi is a prescription medication used to treat certain kinds of myelofibrosis, a condition that causes scar tissue to replace bone marrow. This leads to decreased blood cell production. Jakafi is also used to treat patients with polycythemia vera.

Jakafi belongs to a group of drugs called kinase inhibitors. Jakafi treat certain kinds of myelofibrosis by helping prevent scar tissue from forming in the bone marrow.

Jakafi treats polycythemia vera by inhibiting certain enzymes involved in regulating blood and how your immune system works.

This medication comes in tablet form and is usually taken twice a day, with or without food.

Common side effects of Jakafi include headache and constipation. Jakafi can cause dizziness. Do not drive or operate heavy machinery until you know how Jakafi affects you.

 

Hematology [1]
Reviewed by: 
Anyssa Garza, PharmD [2]
Citation: 
"Jakafi", DailyMed: Current Medication Information; U.S. National Library of Medicine [3] FDA approves Jakafi to treat patients with a chronic type of bone marrow disease. FDA. 2014. [4]
http://www.rxwiki.com/jakafi [5]
Ruxolitinib [6]
Rx Company Link: 
Incyte Corporation [7]
Contributor: 
Anyssa Garza, PharmD [2] Teresa Brucker, Pharm.D [8]
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Jakafi treats certain conditions that affects the bone marrow. Do not drink grapefruit juice while taking Jakafi. Jakafi can cause bruising and dizziness.
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Source URL (retrieved on 06/10/2026 - 18:59): https://www.rxwiki.com/jakafi

Links:
[1] https://www.rxwiki.com/conditions/hematology
[2] https://www.rxwiki.com/users/anyssa-garza-pharmd
[3] http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=f1c82580-87ae-11e0-bc84-0002a5d5c51b
[4] http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm425677.htm?source=govdelivery&utm_medium=email&utm_source=govdelivery
[5] http://www.rxwiki.com/jakafi
[6] https://www.rxwiki.com/ruxolitinib
[7] https://www.rxwiki.com/incyte-corporation
[8] https://www.rxwiki.com/users/teresa-brucker-pharmd