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Emend

Emend is a prescription medication used to prevent nausea and vomiting that may occur within 24 hours after receiving chemotherapy treatment. It is also used with other medications to prevent delayed nausea and vomiting that may occur several days after receiving chemotherapy medications. Emend is also used to prevent nausea and vomiting caused by surgery. Emend  belongs to a group of drugs called antiemetics. These work by blocking the action of neurokinin, a natural substance in the brain that causes nausea and vomiting.

This medication comes as a capsule and an injection.

The capsule is taken by mouth usually once daily, with or without food. To prevent nausea and vomiting due to chemotherapy, you will probably take Emend 1 hour before your first dose of chemotherapy, and then each morning for the next 2 days. To prevent nausea and vomiting caused by surgery, Emend is usually taken as one dose within 3 hours before the start of surgery.

The injection is given either on day 1 with the capsule taken on days 2 and 3 or the injection is given on day 1 and no capsules are taken on the following days. 

Common side effects of the capsule include constipation, itching, and tiredness. Common side effects of the injection include hiccups, tiredness, and changes in liver function blood tests. Do not drive or operate heavy machinery until you know how Emend affects you.

Gastrointestinal [1]
Reviewed by: 
Beth Bolt, RPh [2]
Citation: 
"Emend", DailyMed: Current Medication Information; U.S. National Library of Medicine [3] “Aprepitant,” Medline Plus: Current Medication Information; U.S. National Library of Medicine. [4] "Emend", DailyMed: Current Medication Information; U.S. National Library of Medicine [5]
http://www.rxwiki.com/emend [6]
Aprepitant [7]
Rx Company Link: 
Merck Sharp & Dohme Corp. [8]
RxNorm ATC Ref: 
Other antiemetics [9]
Contributor: 
Teresa Brucker, Pharm.D [10] Anyssa Garza, PharmD [11] Walker Winn [12] Heather Keating [13]
Photo: 
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Long Title: 
Emend prevents nausea and vomiting associated with chemotherapy and surgery. Do not drive or operate heavy machinery until you know how Emend affects you.
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Emend [14]

Source URL (retrieved on 06/09/2026 - 03:52): https://www.rxwiki.com/emend

Links:
[1] https://www.rxwiki.com/conditions/gastrointestinal
[2] https://www.rxwiki.com/users/beth-bolt-rph
[3] http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=696f9e80-9cae-403b-de9e-078343ce4713
[4] http://www.nlm.nih.gov/medlineplus/druginfo/meds/a604003.html#other-uses
[5] http://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=44f634f4-b794-4d55-8ab7-037fdef8ff0f
[6] http://www.rxwiki.com/emend
[7] https://www.rxwiki.com/aprepitant
[8] https://www.rxwiki.com/merck-sharp-dohme-corp
[9] https://www.rxwiki.com/rxnorm-atc/other-antiemetics
[10] https://www.rxwiki.com/users/teresa-brucker-pharmd
[11] https://www.rxwiki.com/users/anyssa-garza-pharmd
[12] https://www.rxwiki.com/users/walker-winn
[13] https://www.rxwiki.com/users/heather-keating
[14] https://www.rxwiki.com/medications/emend