Bydureon is a prescription medication that is used along with diet and exercise to treat type 2 diabetes. Bydureon belongs to a group of medications called incretin mimetics which work by helping the pancreas to secrete insulin when blood sugar levels are high. They also decrease the amount of sugar the liver produces and slow the emptying of the stomach.
Bydureon comes in an injectable form to be given just under the skin (subcutaneous) once a week, at any time of day with or without meals. Bydureon comes in single-dose vials and as single-dose pens. Byderoen BCise comes as single-dose autoinjectors (automatic injecting pens).
Common side effects of Bydureon include nausea, vomiting, diarrhea, and low blood sugar.
WARNING: RISK OF THYROID C-CELL TUMORS
- Bydureon causes an increased incidence in thyroid C-cell tumors at clinically relevant exposures in rats compared to controls. It is unknown whether Bydureon causes thyroid C-cell tumors, including medullary thyroid carcinoma (MTC), in humans, as human relevance could not be determined by clinical or nonclinical studies.
- Bydureon is contraindicated in patients with a personal or family history of MTC and in patients with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). Routine serum calcitonin or thyroid ultrasound monitoring is of uncertain value in patients treated with Bydureon. Patients should be counseled regarding the risk and symptoms of thyroid tumors.
Review Date:
June 25, 2012 Citation:
"Bydureon", DailyMed: Current Medication Information; U.S. National Library of Medicine [4]
Exenatide [6]
Contributor:
Teresa Brucker, Pharm.D [9] Beth Bolt, RPh [3] Eric Ho, Pharm.D [10] Anyssa Garza, PharmD [11] Walker Winn [12] Zach Lewitz [13] Photo:
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Bydureon treats type 2 diabetes. Can cause nausea. Nausea most commonly happens when first starting Bydureon, but may become less over time. Black Box Warning Image:
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