Preparation H Cream

Preparation H Cream provides rapid, soothing relief from pain, burning, itching and discomfort associated with hemorrhoids. Ask your doctor before using this product if you have high blood pressure.

Preparation H Cream Overview


Preparation H Cream is an over the counter medication used to provide prompt, temporary relief from painful burning, itching and discomfort of hemorrhoids.

It is a single product containing 4 ingredients: glycerin, pramoxine, white petrolatum, and phenylephrine. 

Pramoxine is an anesthetic, or "numbing medicine." It works by interfering with pain signals sent from the nerves to the brain.

Phenylephrine belongs to a group of drugs called vasoconstrictors. These work by temporarily shrinking swollen hemorrhoidal tissue.

Glycerin and white petrolatum are protectants. These work to protect the inflamed, irritated anorectal surface to help make bowel movements less painful.

This medication comes in a cream and is applied externally to the affected area up to 4 times daily, especially at night, in the morning or after each bowel movement.

Common side effects of Preparation H Cream include mild pain or stinging.


Patient Ratings for Preparation H Cream

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What are you taking Preparation H Cream for?

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  • Other
  • Constipation
  • Dermatitis
  • Dermatitis, Contact
  • Fissure In Ano
  • Glaucoma, Open-angle
  • Hemorrhoids
  • Hypotension
  • Pain
  • Pruritus
  • Pruritus Ani
  • Rhinitis, Vasomotor
  • Shock, Septic
  • Tachycardia, Supraventricular

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  • Less than a week
  • A couple weeks
  • A month or so
  • A few months
  • A year or so
  • Two years or more

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Preparation H Cream consists of multiple generic medications. The generic medications are listed below.


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For more information on this medication choose from the list of selections below.


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Preparation H Cream Drug Class

Preparation H Cream is part of the drug class: