Pregnyl

Pregnyl is used to promote descent of the testicles in young boys, hormone production in men, and ovulation and pregnancy in women. Pregnyl is given as an injection into the muscle by a physician.

Pregnyl Overview

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Pregnyl is a prescription medication used to promote descent of the testicles in young boys, hormone production in men, and ovulation and pregnancy in women. Pregnyl belongs to a group of drugs called synthetic hormones, which work by helping to balance the levels of natural hormones in the body.

This medication comes in injectable form and is typically given three times per week directly into the muscle by a healthcare professional. 

Common side effects of Pregnyl include headache, irritability, and restlessness.

 

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Pregnyl Cautionary Labels

precautionsprecautionsprecautionsprecautionsprecautionsprecautions

Uses of Pregnyl

Pregnyl is a prescription medication used to promote descent of the testicles in young boys, hormone production in men, and ovulation and pregnancy in women.

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

Manufacturer

Chorionic Gonadotrophin

For more information on this medication choose from the list of selections below.

Pregnyl Drug Class

Pregnyl is part of the drug class:

Side Effects of Pregnyl

Serious side effects have been reported with Pregnyl. See the “Pregnyl Precautions” section.

Common side effects of Pregnyl include the following:

  • headache
  • irritability
  • restlessness
  • depression
  • tiredness
  • edema
  • early-onset puberty
  • swelling of breast tissue
  • pain at the site of injection

This is not a complete list of Pregnyl side effects. Ask your doctor or pharmacist for more information.

Tell your doctor if you have any side effect that bothers you or that does not go away.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Pregnyl Interactions

No drug interactions have been determined by the manufacturer. However, you should tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. Not all drug interactions are known or reported and new drug interactions are continually being reported.

Pregnyl Precautions

Serious side effects have been reported with Pregnyl including the following:

  • Life-threatening allergic reactions. Discontinue using Pregnyl and get medical attention immediately if you experience facial, lip, tongue, throat swelling and/or difficulty breathing.
  • Hyperstimulation and/or enlargement of the ovaries. Discontinue using Pregnyl and get medical attention immediately if you experience abnormal severe abdominal pain.
  • Full body swelling. Discontinue using Pregnyl and get medical attention immediately if you experience abnormal swelling of your extremities and/or abdomen.
  • Fluid in the lungs. Discontinue using Pregnyl and get medical attention immediately if you experience sudden difficultly breathing.
  • Early-onset puberty. Discontinue using Pregnyl and get medical attention immediately if you or your child experiences symptoms of early-onset puberty including increased hair growth and thickening, deepening of the voice, acne, early breast development, and/or rapid height growth.

Do not take Pregnyl if you:

  • Are allergic to Pregnyl or to any of its ingredients
  • Have early-onset puberty
  • Have prostate cancer
  • Have other cancers that are stimulated by androgens

Pregnyl Food Interactions

Medications can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of Pregnyl, there are no specific foods that you must exclude from your diet when receiving this medication.

Inform MD

Before taking Pregnyl, tell your doctor about all of your medical conditions. Especially tell your doctor if you:

  • are allergic to Pregnyl or to any of its ingredients
  • have early-onset puberty
  • have asthma
  • have epilepsy
  • have heart disease
  • have kidney disease
  • have prostate cancer or any other cancers that are stimulated by androgens
  • are pregnant or plan to become pregnant
  • are breastfeeding or plan to breastfeed

Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements.

Pregnyl and Pregnancy

Tell your doctor if you are pregnant or plan to become pregnant.

The FDA categorizes medications based on safety for use during pregnancy. Five categories - A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy.

Pregnyl falls into category X. It has been shown that women taking Pregnyl during pregnancy may have babies born with problems. There are no situations where the benefits of the medication for the mother outweigh the risks of harm to the baby. These medicines should never be used by pregnant women.

Pregnyl and Lactation

Tell your doctor if you are breastfeeding or plan to breastfeed.

It is not known if Pregnyl crosses into human milk. Because many medications can cross into human milk and because of the possibility for serious adverse reactions in nursing infants with use of this medication, a choice should be made whether to stop nursing or stop the use of this medication. Your doctor and you will decide if the benefits outweigh the risk of using Pregnyl.

Pregnyl Usage

Take Pregnyl exactly as prescribed.

This medication is available in an injectable form to be given directly into a muscle (IM) by a healthcare professional typically three times per week.

If you miss a dose, receive the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and receive your next dose at the regular time. Do not receive two doses of Pregnyl at the same time.

 

Pregnyl Dosage

Take this medication exactly as prescribed by your doctor. Follow the directions on your prescription label carefully.

The dose your doctor recommends may be based on the following:

  • the condition being treated
  • other medical conditions you have
  • other medications you are taking
  • how you respond to this medication
  • your weight
  • your height
  • your age
  • your gender

The recommended dose of Pregnyl to promote descent of the testicles in young boys is:

  1. 4000 units 3 times weekly for 3 weeks
  2. Then, 5000 units every second day for 4 injections
  3. Then, 15 injections for 500 to 1000 units over a period of 6 weeks
  4. Then, 500 units 3 times weekly for 4 to 6 weeks.
  5. If this course of treatment is not successful, another series is begun 1 month later, giving 1000 units per injection

The recommended dose of Pregnyl to promote hormone production in men is:

  1. 500 to 1000 units 3 times a week for 3 weeks, followed by the same dose twice a week for 3 weeks
  2. Then, 4000 units 3 times weekly for 6 to 9 months, following which the dosage may be reduced to 2000 units 3 times weekly for an additional 3 months

The recommended dose range of Pregnyl to promote ovulation and pregnancy in women is:

  • 5000 to 10,000 USP units given once

Pregnyl Overdose

If Pregnyl is administered by a healthcare provider in a medical setting, it is unlikely that an overdose will occur. However, if overdose is suspected, seek emergency medical attention.

Other Requirements

  • Store at controlled room temperature 15–30°C (59–86°F).
  • Reconstituted solution is stable for 60 days when refrigerated.
  • Keep this and all medicines out of the reach of children.